Literature DB >> 26582234

Regulating Factors in Acid-Sensing Ion Channel 1a Function.

Yinghong Wang1, Zaven O'Bryant2, Huan Wang1, Yan Huang3.   

Abstract

In recent years, research of acid sensing ion channels (ASICs) has increased tremendously, especially studies focusing on ASIC1a, which plays a critical role in many important physiologic and pathological functions. This review will discuss factors regulating ASIC1a expression and activity in various conditions and will provide a theoretical basis for clinical development and application of ASIC1a modifiers.

Keywords:  ASICs; Ion channels; Neuronal injury; Pharmacology; Stroke

Mesh：

Substances：

Year:  2015        PMID： 26582234     DOI： 10.1007/s11064-015-1768-x

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  147 in total

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2.  Modulation of acid-sensing ion channels by Cu(2+) in cultured hypothalamic neurons of the rat.

Authors:  W Wang; Y Yu; T-L Xu
Journal:  Neuroscience       Date:  2007-01-16       Impact factor: 3.590

3.  Evidence for neuroprotection by the fenamate NSAID, mefenamic acid.

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4.  Acid-sensing ion channels in acidosis-induced injury of human brain neurons.

Authors:  Minghua Li; Koichi Inoue; Deborah Branigan; Eric Kratzer; Jillian C Hansen; Jeff W Chen; Roger P Simon; Zhi-Gang Xiong
Journal:  J Cereb Blood Flow Metab       Date:  2010-03-10       Impact factor: 6.200

5.  Identification of tissue kallikrein in brain and in the cell-free translation product encoded by brain mRNA.

Authors:  J Chao; C Woodley; L Chao; H S Margolius
Journal:  J Biol Chem       Date:  1983-12-25       Impact factor: 5.157

6.  Zn2+ and H+ are coactivators of acid-sensing ion channels.

Authors:  A Baron; L Schaefer; E Lingueglia; G Champigny; M Lazdunski
Journal:  J Biol Chem       Date:  2001-07-16       Impact factor: 5.157

Review 7.  The pharmacology of sigma-1 receptors.

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Journal:  Pharmacol Ther       Date:  2009-07-18       Impact factor: 12.310

8.  Potentiation of acid-sensing ion channels by sulfhydryl compounds.

Authors:  Jun-Hyeong Cho; Candice C Askwith
Journal:  Am J Physiol Cell Physiol       Date:  2007-03-28       Impact factor: 4.249

9.  Rabbit retinal neurons and glia express a variety of ENaC/DEG subunits.

Authors:  L M Brockway; Z-H Zhou; J K Bubien; B Jovov; D J Benos; K T Keyser
Journal:  Am J Physiol Cell Physiol       Date:  2002-07       Impact factor: 4.249

10.  Expression of acid-sensing ion channels in nucleus pulposus cells of the human intervertebral disk is regulated by non-steroid anti-inflammatory drugs.

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Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2014-07-30       Impact factor: 3.848
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Review 3.  Acid-Sensing Ion Channel-1a in Articular Chondrocytes and Synovial Fibroblasts: A Novel Therapeutic Target for Rheumatoid Arthritis.

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4.  The Role of ASIC1a in Inflammatory Immune Diseases: A Potential Therapeutic Target.

Authors:  Yinghong Wang; Xiaojie Hu; Yancai Sun; Yan Huang
Journal:  Front Pharmacol       Date:  2022-07-08       Impact factor: 5.988

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