Literature DB >> 26581865

Properties of VIP+ synapses in the suprachiasmatic nucleus highlight their role in circadian rhythm.

Nathan P Achilly1.   

Abstract

Circadian rhythms coordinate cyclical behavioral and physiological changes in most organisms. In humans, this biological clock is located within the suprachiasmatic nucleus (SCN) of the hypothalamus and consists of a heterogeneous neuron population characterized by their enriched expression of various neuropeptides. As highlighted here, Fan et al. (J Neurosci 35: 1905-1029, 2015) developed an elegant experimental system to investigate the synaptic properties of vasoactive intestinal peptide (VIP)-expressing neurons between day and night, and further delineate their broader architecture and function within the SCN.
Copyright © 2016 the American Physiological Society.

Entities:  

Keywords:  GABA; SCN; VIP; circadian rhythm

Mesh:

Substances:

Year:  2015        PMID: 26581865      PMCID: PMC4922597          DOI: 10.1152/jn.00393.2015

Source DB:  PubMed          Journal:  J Neurophysiol        ISSN: 0022-3077            Impact factor:   2.714


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