Literature DB >> 26581702

Conservative treatment in a patient with diabetic osteomyelitis: antibiotic treatment is sufficient for complete bone regeneration in selected cases.

Sune Møller Jeppesen1, Johnny Frøkjær2, Knud Yderstræde3.   

Abstract

Diabetic foot ulcers are commonly complicated by bone involvement and osteomyelitis. Diagnosing diabetic osteomyelitis can be problematic. However, positive findings at clinical examination and X-ray may set the diagnosis. Recent guidelines suggest that selected cases of diabetic osteomyelitis can be treated conservatively with antibiotics. We report on the successful treatment of a 52-year-old man with diabetes with osteomyelitis in the distal phalanx of a toe. On X-ray, the affected phalanx appeared completely eroded. However, regeneration of the bone tissue was observed following outpatient treatment with antibiotics. We therefore encourage doctors to provide conservative treatment for selected cases of diabetic osteomyelitis. 2015 BMJ Publishing Group Ltd.

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Year:  2015        PMID: 26581702      PMCID: PMC4654164          DOI: 10.1136/bcr-2015-211376

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  8 in total

1.  Role of bone biopsy specimen culture in the management of diabetic foot osteomyelitis.

Authors:  T P Elamurugan; S Jagdish; Vikram Kate; Subhash Chandra Parija
Journal:  Int J Surg       Date:  2010-12-01       Impact factor: 6.071

Review 2.  Diagnosis and management of infection in the diabetic foot.

Authors:  Edgar J G Peters; Benjamin A Lipsky
Journal:  Med Clin North Am       Date:  2013-06-05       Impact factor: 5.456

3.  Deep wound cultures correlate well with bone biopsy culture in diabetic foot osteomyelitis.

Authors:  M Malone; F L Bowling; A Gannass; E B Jude; A J M Boulton
Journal:  Diabetes Metab Res Rev       Date:  2013-10       Impact factor: 4.876

4.  Treating diabetic foot osteomyelitis primarily with surgery or antibiotics: have we answered the question?

Authors:  Benjamin A Lipsky
Journal:  Diabetes Care       Date:  2014       Impact factor: 19.112

5.  Diagnosing diabetic foot osteomyelitis: is the combination of probe-to-bone test and plain radiography sufficient for high-risk inpatients?

Authors:  J Aragón-Sánchez; Benjamin A Lipsky; J L Lázaro-Martínez
Journal:  Diabet Med       Date:  2011-02       Impact factor: 4.359

6.  Six-week versus twelve-week antibiotic therapy for nonsurgically treated diabetic foot osteomyelitis: a multicenter open-label controlled randomized study.

Authors:  Alina Tone; Sophie Nguyen; Fabrice Devemy; Hélène Topolinski; Michel Valette; Marie Cazaubiel; Armelle Fayard; Éric Beltrand; Christine Lemaire; Éric Senneville
Journal:  Diabetes Care       Date:  2014-11-20       Impact factor: 19.112

Review 7.  Apoptosis-associated uncoupling of bone formation and resorption in osteomyelitis.

Authors:  Ian Marriott
Journal:  Front Cell Infect Microbiol       Date:  2013-12-19       Impact factor: 5.293

8.  An 11-year-old male with refractory osteomyelitis.

Authors:  Clifford T Mauriello; Ole A Raustol; Maria A Aguiar; Kenji M Cunnion
Journal:  Case Rep Pediatr       Date:  2012-12-03
  8 in total

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