Literature DB >> 26581518

Control of telomerase action at human telomeres.

Dirk Hockemeyer1,2, Kathleen Collins1,2.   

Abstract

Recent progress has greatly increased the understanding of telomere-bound shelterin proteins and the telomerase holoenzyme, predominantly as separate complexes. Pioneering studies have begun to investigate the requirements for shelterin-telomerase interaction. From this vantage point, focusing on human cells, we review and discuss models for how telomerase and shelterin subunits coordinate to achieve balanced telomere-length homeostasis.

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Year:  2015        PMID： 26581518      PMCID： PMC4765361          DOI： 10.1038/nsmb.3083

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  83 in total

1.  Dynamics of protein binding to telomeres in living cells: implications for telomere structure and function.

Authors:  Karin A Mattern; Susan J J Swiggers; Alex L Nigg; Bob Löwenberg; Adriaan B Houtsmuller; J Mark J M Zijlmans
Journal:  Mol Cell Biol       Date:  2004-06       Impact factor: 4.272

2.  Control of telomere length by the human telomeric protein TRF1.

Authors:  B van Steensel; T de Lange
Journal:  Nature       Date:  1997-02-20       Impact factor: 49.962

3.  Lack of cell cycle regulation of telomerase activity in human cells.

Authors:  S E Holt; D L Aisner; J W Shay; W E Wright
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

4.  Mammalian telomeres end in a large duplex loop.

Authors:  J D Griffith; L Comeau; S Rosenfield; R M Stansel; A Bianchi; H Moss; T de Lange
Journal:  Cell       Date:  1999-05-14       Impact factor: 41.582

5.  Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.

Authors:  S L Weinrich; R Pruzan; L Ma; M Ouellette; V M Tesmer; S E Holt; A G Bodnar; S Lichtsteiner; N W Kim; J B Trager; R D Taylor; R Carlos; W H Andrews; W E Wright; J W Shay; C B Harley; G B Morin
Journal:  Nat Genet       Date:  1997-12       Impact factor: 38.330

6.  TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.

Authors:  Jeffrey Zheng-Sheng Ye; Jill R Donigian; Megan van Overbeek; Diego Loayza; Yan Luo; Andrew N Krutchinsky; Brian T Chait; Titia de Lange
Journal:  J Biol Chem       Date:  2004-08-16       Impact factor: 5.157

7.  A common sequence motif determines the Cajal body-specific localization of box H/ACA scaRNAs.

Authors:  Patricia Richard; Xavier Darzacq; Edouard Bertrand; Beáta E Jády; Céline Verheggen; Tamás Kiss
Journal:  EMBO J       Date:  2003-08-15       Impact factor: 11.598

8.  POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.

Authors:  Jeffrey Zheng-Sheng Ye; Dirk Hockemeyer; Andrew N Krutchinsky; Diego Loayza; Sarah M Hooper; Brian T Chait; Titia de Lange
Journal:  Genes Dev       Date:  2004-07-01       Impact factor: 11.361

Review 9.  Regulation of telomerase by telomeric proteins.

Authors:  Agata Smogorzewska; Titia de Lange
Journal:  Annu Rev Biochem       Date:  2004       Impact factor: 23.643

10.  Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal.

Authors:  Beáta E Jády; Edouard Bertrand; Tamás Kiss
Journal:  J Cell Biol       Date:  2004-02-23       Impact factor: 10.539
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  56 in total

Review 1.  Telomerase Mechanism of Telomere Synthesis.

Authors:  R Alex Wu; Heather E Upton; Jacob M Vogan; Kathleen Collins
Journal:  Annu Rev Biochem       Date:  2017-01-30       Impact factor: 23.643

Review 2.  Integrative structural biology of Tetrahymena telomerase - insights into catalytic mechanism and interaction at telomeres.

Authors:  Juli Feigon; Henry Chan; Jiansen Jiang
Journal:  FEBS J       Date:  2016-03-17       Impact factor: 5.542

Review 3.  Telomerase structures and regulation: shedding light on the chromosome end.

Authors:  Thi Hoang Duong Nguyen; Kathleen Collins; Eva Nogales
Journal:  Curr Opin Struct Biol       Date:  2019-06-12       Impact factor: 6.809

4.  DNA-binding determinants and cellular thresholds for human telomerase repeat addition processivity.

Authors:  Robert Alexander Wu; Jane Tam; Kathleen Collins
Journal:  EMBO J       Date:  2017-05-11       Impact factor: 11.598

Review 5.  Shaping human telomeres: from shelterin and CST complexes to telomeric chromatin organization.

Authors:  Ci Ji Lim; Thomas R Cech
Journal:  Nat Rev Mol Cell Biol       Date:  2021-02-09       Impact factor: 94.444

Review 6.  Telomeres in cancer: tumour suppression and genome instability.

Authors:  John Maciejowski; Titia de Lange
Journal:  Nat Rev Mol Cell Biol       Date:  2017-01-18       Impact factor: 94.444

7.  Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes.

Authors:  Heather E Upton; Henry Chan; Juli Feigon; Kathleen Collins
Journal:  J Biol Chem       Date:  2016-11-28       Impact factor: 5.157

8.  Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo.

Authors:  Kunitoshi Chiba; Jacob M Vogan; Robert A Wu; Manraj S Gill; Xiaozhu Zhang; Kathleen Collins; Dirk Hockemeyer
Journal:  Mol Cell Biol       Date:  2017-01-19       Impact factor: 4.272

9.  Active Yeast Telomerase Shares Subunits with Ribonucleoproteins RNase P and RNase MRP.

Authors:  Bruno Lemieux; Nancy Laterreur; Anna Perederina; Jean-François Noël; Marie-Line Dubois; Andrey S Krasilnikov; Raymund J Wellinger
Journal:  Cell       Date:  2016-05-05       Impact factor: 41.582

10.  The Drosophila telomere-capping protein Verrocchio binds single-stranded DNA and protects telomeres from DNA damage response.

Authors:  Alessandro Cicconi; Emanuela Micheli; Fiammetta Vernì; Alison Jackson; Ana Citlali Gradilla; Francesca Cipressa; Domenico Raimondo; Giuseppe Bosso; James G Wakefield; Laura Ciapponi; Giovanni Cenci; Maurizio Gatti; Stefano Cacchione; Grazia Daniela Raffa
Journal:  Nucleic Acids Res       Date:  2017-04-07       Impact factor: 16.971
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