Literature DB >> 26581234

To intervene or not? A man with multidrug-resistant hypertension, endovascular abdominal aneurysm repair, bilateral renal artery stenosis and end-stage renal disease salvaged with renal artery stenting.

Pantelis A Sarafidis1, Kyriakos C Stavridis2, Charalampos N Loutradis1, Athanasios N Saratzis3, Panagiotis Pateinakis4, Aikaterini Papagianni1, Georgios Efstratiadis1, Nicolaos Saratzis2.   

Abstract

We report the case of a 69-year-old man with uncontrolled multidrug-resistant secondary hypertension following a 10 year history of endovascular abdominal aortic aneurysm repair, with suprarenal fixation and concurrent angioplasty with stenting of the left renal artery for atherosclerotic renal disease, and progressive chronic kidney disease. Renal scintigraphy revealed complete loss of the right kidney's and severe reduction of the left kidney's perfusion and function. Following recent evidence and consultation with vascular surgeons regarding the technical difficulties of any procedure, escalation of antihypertensive treatment was initially chosen. Careful drug adjustments significantly improved but did not fully control blood pressure (BP); further, the patient experienced an acute ischaemic stroke and renal function deterioration towards end-stage renal disease within a few months. At this point, revascularization of the left renal artery coupled with three haemodialysis sessions to remove contrast media was justified as rescue therapy against permanent renal replacement therapy. Successful intervention achieved an immediate BP reduction, with BP fully controlled, despite a  > 70% decrease in antihypertensive treatment, while renal function improved at 6 months from 11.5 to 22 ml/min/1.73 m(2). Renal angioplasty confers undisputed benefits in BP control and nephroprotection, and should be offered without delay to patients with renovascular hypertension and/or ischaemic nephropathy.

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Keywords:  Atherosclerotic renal disease; chronic kidney disease; ischaemic nephropathy; renal artery stenosis; secondary hypertension

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Year:  2015        PMID: 26581234     DOI: 10.3109/08037051.2015.1110926

Source DB:  PubMed          Journal:  Blood Press        ISSN: 0803-7051            Impact factor:   2.835


  2 in total

Review 1.  Renal Artery Stenosis in Patients with Resistant Hypertension: Stent It or Not?

Authors:  Patricia Van der Niepen; Patrick Rossignol; Jean-Philippe Lengelé; Elena Berra; Pantelis Sarafidis; Alexandre Persu
Journal:  Curr Hypertens Rep       Date:  2017-01       Impact factor: 5.369

2.  Renal artery stenting of chronic kidney disease patient with resistant hypertension.

Authors:  Ali Çoner; Davran Çiçek; Sinan Akıncı; Haldun Müderrisoğlu
Journal:  Anatol J Cardiol       Date:  2016-11       Impact factor: 1.596

  2 in total

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