Literature DB >> 2658061

Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum.

C M Wilson1, A E Serrano, A Wasley, M P Bogenschutz, A H Shankar, D F Wirth.   

Abstract

The malaria parasite Plasmodium falciparum contains at least two genes related to the mammalian multiple drug resistance genes, and at least one of the P. falciparum genes is expressed at a higher level and is present in higher copy number in a strain that is resistant to multiple drugs than in a strain that is sensitive to the drugs.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2658061     DOI： 10.1126/science.2658061

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  102 in total

1.  Genetics of mefloquine resistance in the rodent malaria parasite Plasmodium chabaudi.

Authors:  Pedro V L Cravo; Jane M-R Carlton; Paul Hunt; Laura Bisoni; Rose Ann Padua; David Walliker
Journal:  Antimicrob Agents Chemother       Date:  2003-02       Impact factor: 5.191

2.  Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya.

Authors:  Abigael Mbaisi; Pamela Liyala; Fredrick Eyase; Rachel Achilla; Hosea Akala; Julia Wangui; Josphat Mwangi; Finnley Osuna; Uzma Alam; Bonnie L Smoak; Jon M Davis; Dennis E Kyle; Rodney L Coldren; Carl Mason; Norman C Waters
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

Review 3.  Active efflux mechanisms for antimicrobial resistance.

Authors:  S B Levy
Journal:  Antimicrob Agents Chemother       Date:  1992-04       Impact factor: 5.191

4.  Variations in frequencies of drug resistance in Plasmodium falciparum.

Authors:  P K Rathod; T McErlean; P C Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-19       Impact factor: 11.205

Review 5.  Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.

Authors:  Robert L Summers; Megan N Nash; Rowena E Martin
Journal:  Cell Mol Life Sci       Date:  2012-06       Impact factor: 9.261

6.  Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum.

Authors:  Petra Rohrbach; Cecilia P Sanchez; Karen Hayton; Oliver Friedrich; Jigar Patel; Amar Bir Singh Sidhu; Michael T Ferdig; David A Fidock; Michael Lanzer
Journal:  EMBO J       Date:  2006-06-22       Impact factor: 11.598

7.  marA, a regulated locus which controls expression of chromosomal multiple antibiotic resistance in Escherichia coli.

Authors:  H Hächler; S P Cohen; S B Levy
Journal:  J Bacteriol       Date:  1991-09       Impact factor: 3.490

8.  Isolation and characterization of Drosophila multidrug resistance gene homologs.

Authors:  C T Wu; M Budding; M S Griffin; J M Croop
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

9.  Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Authors:  David J Johnson; David A Fidock; Mathirut Mungthin; Viswanathan Lakshmanan; Amar Bir Singh Sidhu; Patrick G Bray; Stephen A Ward
Journal:  Mol Cell       Date:  2004-09-24       Impact factor: 17.970

10.  Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina.

Authors:  G R Cutting; L Lu; B F O'Hara; L M Kasch; C Montrose-Rafizadeh; D M Donovan; S Shimada; S E Antonarakis; W B Guggino; G R Uhl
Journal:  Proc Natl Acad Sci U S A       Date:  1991-04-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.