Literature DB >> 26577512

Intralesional 5-fluorouracil (FU) as a treatment for nonmelanoma skin cancer (NMSC): A review.

Lauren Metterle1, Christopher Nelson1, Nishit Patel2.   

Abstract

The treatment paradigm for nonmelanoma skin cancer remains surgical. This fact combined with its remarkably high incidence positions it as the fifth most costly cancer to treat in the Medicare population. To address this, consideration of alternative medical therapeutics is warranted. Intralesional 5-fluorouracil is a potentially affordable option that may demand further investigation. This literature review examines current data on its efficacy and adverse effects.
Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  5-fluorouracil; basal cell carcinoma; intralesional; management; medical therapy; nonmelanoma skin cancer; squamous cell carcinoma

Mesh：

Substances：

Year:  2015        PMID： 26577512     DOI： 10.1016/j.jaad.2015.09.040

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN： 0190-9622            Impact factor:   11.527


  9 in total

Review 1.  Research gaps in the management and prevention of cutaneous squamous cell carcinoma in organ transplant recipients.

Authors:  M Blomberg; S Y He; C Harwood; S T Arron; S Demehri; A Green; M M Asgari
Journal:  Br J Dermatol       Date:  2017-10-30       Impact factor: 9.302

2.  Consensus Guidelines on the Use of Superficial Radiation Therapy for Treating Nonmelanoma Skin Cancers and Keloids.

Authors:  Mark S Nestor; Brian Berman; David Goldberg; Armand B Cognetta; Michael Gold; William Roth; Clay J Cockerell; Brad Glick
Journal:  J Clin Aesthet Dermatol       Date:  2019-02-01

3.  Theoretical study of gallium nitride nanocage as a carrier for 5-fluorouracil anticancer drug.

Authors:  Nuha Wazzan; Kamal A Soliman; W S Abdel Halim
Journal:  J Mol Model       Date:  2019-08-23       Impact factor: 1.810

Review 4.  Emerging Perspective: Role of Increased ROS and Redox Imbalance in Skin Carcinogenesis.

Authors:  Dehai Xian; Rui Lai; Jing Song; Xia Xiong; Jianqiao Zhong
Journal:  Oxid Med Cell Longev       Date:  2019-09-16       Impact factor: 6.543

5.  Triple therapy with intralesional 5-fluorouracil, chemowraps, and acitretin: A well-tolerated option for treatment of widespread cutaneous squamous cell carcinomas on the legs.

Authors:  Iviensan F Manalo; Michael C Lowe; Kelly C Nelson; Suephy C Chen
Journal:  JAAD Case Rep       Date:  2019-11-20

Review 6.  Pathogenesis of Keratinocyte Carcinomas and the Therapeutic Potential of Medicinal Plants and Phytochemicals.

Authors:  Andrea Jess Josiah; Danielle Twilley; Sreejarani Kesavan Pillai; Suprakas Sinha Ray; Namrita Lall
Journal:  Molecules       Date:  2021-04-01       Impact factor: 4.411

7.  Synthesis, biological evaluation and docking studies of 1,2,4-oxadiazole linked 5-fluorouracil derivatives as anticancer agents.

Authors:  Ravi Kumar Bommera; Shashikala Kethireddy; Rajeshwar Reddy Govindapur; Laxminarayana Eppakayala
Journal:  BMC Chem       Date:  2021-05-04

8.  Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative.

Authors:  Çinel Köksal Karayildirim; Mustafa Kotmakçi; Erkan Halay; Kadir Ay; Yücel Başpinar
Journal:  Saudi Pharm J       Date:  2018-01-10       Impact factor: 4.330

Review 9.  Neoadjuvant Therapy for Non-melanoma Skin Cancer: Updated Therapeutic Approaches for Basal, Squamous, and Merkel Cell Carcinoma.

Authors:  Enrico Zelin; Iris Zalaudek; Marina Agozzino; Caterina Dianzani; Arianna Dri; Nicola Di Meo; Roberta Giuffrida; Giovanni Francesco Marangi; Nicoleta Neagu; Paolo Persichetti; Ludovica Toffoli; Claudio Conforti
Journal:  Curr Treat Options Oncol       Date:  2021-03-16
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.