Literature DB >> 26577432

Predictive value of C-reactive protein, ultrasound and Alvarado score in acute appendicitis: a prospective pediatric cohort.

Mohamed Zouari1, Mohamed Jallouli2, Hamdi Louati2, Rim Kchaou2, Rahma Chtourou2, Ahmed Kotti2, Mahdi Ben Dhaou2, Hayet Zitouni2, Riadh Mhiri2.   

Abstract

PURPOSE: To evaluate whether C-reactive protein (CRP) level and ultrasound (US) results on admission could aid the diagnostic accuracy of Alvarado score.
METHODS: A prospective study was performed on children <14 years admitted for suspected acute appendicitis. Patients were categorized into three groups based on the Alvarado score: group I: score 7-10, group II: score 5-6, group III: score 0-4.
RESULTS: The difference between predictive values of Alvarado score alone and Alvarado score with CRP was not statically significant. The PPV increased from 74.29% (Alvarado score and CRP) to 93.75% (Alvarado score and US) in group 1 (P = .001) and the NPV increased from 64.86 and 79.69% (Alvarado score and CRP) to 82.6 and 88.2% (Alvarado score and US) in group 2 (P = .01) and group 3 (P = .001), respectively.
CONCLUSIONS: Alvarado score and ultrasound taken together improve the predictive value of diagnosing acute appendicitis in children.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID: 26577432     DOI: 10.1016/j.ajem.2015.10.004

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  5 in total

Review 1.  Pediatric emergency medicine point-of-care ultrasound: summary of the evidence.

Authors:  Jennifer R Marin; Alyssa M Abo; Alexander C Arroyo; Stephanie J Doniger; Jason W Fischer; Rachel Rempell; Brandi Gary; James F Holmes; David O Kessler; Samuel H F Lam; Marla C Levine; Jason A Levy; Alice Murray; Lorraine Ng; Vicki E Noble; Daniela Ramirez-Schrempp; David C Riley; Turandot Saul; Vaishali Shah; Adam B Sivitz; Ee Tein Tay; David Teng; Lindsey Chaudoin; James W Tsung; Rebecca L Vieira; Yaffa M Vitberg; Resa E Lewiss
Journal:  Crit Ultrasound J       Date:  2016-11-03

2.  Diagnostic accuracy of combining C-Reactive protein and Alvarado Score among 2-to-20-year-old patients with acute appendicitis suspected presenting to Emergency Departments.

Authors:  K Altali Alhames; F J Martín-Sánchez; P Ruiz-Artacho; F J Ayuso; V Trenchs; M Martínez Ortiz de Zarate; C Navarro; M Fuentes Ferrer; C Fernández; J González Del Castillo; A Bodas
Journal:  Rev Esp Quimioter       Date:  2021-04-30       Impact factor: 1.553

3.  Ultrasound for Appendicitis: Performance and Integration with Clinical Parameters.

Authors:  Fanny Löfvenberg; Martin Salö
Journal:  Biomed Res Int       Date:  2016-12-01       Impact factor: 3.411

4.  Which One is Better? Comparison of the Acute Inflammatory Response, Raja Isteri Pengiran Anak Saleha Appendicitis and Alvarado Scoring Systems.

Authors:  Mohammad Yasin Karami; Hadi Niakan; Navid Zadebagheri; Parviz Mardani; Zahra Shayan; Iman Deilami
Journal:  Ann Coloproctol       Date:  2017-12-31

5.  Is the platelet to lymphocyte ratio a promising biomarker to distinguish acute appendicitis? Evidence from a systematic review with meta-analysis.

Authors:  Lianjie Liu; Zhuo Shao; Hang Yu; Wei Zhang; Hao Wang; Zubing Mei
Journal:  PLoS One       Date:  2020-05-22       Impact factor: 3.240

  5 in total

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