Literature DB >> 26575137

The Triaging and Treatment of Cold-Induced Injuries.

Christoph Sachs1, Marcus Lehnhardt, Adrien Daigeler, Ole Goertz.   

Abstract

BACKGROUND: In Central Europe, cold-induced injuries are much less common than burns. In a burn center in western Germany, the mean ratio of these two types of injury over the past 10 years was 1 to 35. Because cold-induced injuries are so rare, physicians often do not know how to deal with them.
METHODS: This article is based on a review of publications (up to December 2014) retrieved by a selective search in PubMed using the terms "freezing," "frostbite injury," "non-freezing cold injury," and "frostbite review," as well as on the authors' clinical experience.
RESULTS: Freezing and cold-induced trauma are part of the treatment spectrum in burn centers. The treatment of cold-induced injuries is not standardized and is based largely on case reports and observations of use. distinction is drawn between non-freezing injuries, in which there is a slow temperature drop in tissue without freezing, and freezing injuries in which ice crystals form in tissue. In all cases of cold-induced injury, the patient should be slowly warmed to 22°-27°C to prevent reperfusion injury. Freezing injuries are treated with warming of the body's core temperature and with the bathing of the affected body parts in warm water with added antiseptic agents. Any large or open vesicles that are already apparent should be debrided. To inhibit prostaglandin-mediated thrombosis, ibuprofen is given (12 mg/kg body weight b.i.d.).
CONCLUSION: The treatment of cold-induced injuries is based on their type, severity, and timing. The recommendations above are grade C recommendations. The current approach to reperfusion has yielded promising initial results and should be further investigated in prospective studies.

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Year:  2015        PMID: 26575137      PMCID: PMC4650908          DOI: 10.3238/arztebl.2015.0741

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  46 in total

Review 1.  Frostbite: pathogenesis and treatment.

Authors:  J V Murphy; P E Banwell; A H Roberts; D A McGrouther
Journal:  J Trauma       Date:  2000-01

2.  Role of core temperature as a stimulus for cold acclimation during repeated immersion in 20 degrees C water.

Authors:  C O'Brien; A J Young; D T Lee; A Shitzer; M N Sawka; K B Pandolf
Journal:  J Appl Physiol (1985)       Date:  2000-07

3.  Position paper: on-site treatment of frostbite for mountaineers.

Authors:  David Syme
Journal:  High Alt Med Biol       Date:  2002       Impact factor: 1.981

4.  An open-label study to evaluate the safety and efficacy of tissue plasminogen activator in treatment of severe frostbite.

Authors:  John A Twomey; George L Peltier; Richard T Zera
Journal:  J Trauma       Date:  2005-12

5.  Influence of ISDN, L-NAME and selenium on microcirculation, leukocyte endothelium interaction and angiogenesis after frostbite.

Authors:  O Goertz; H Haddad; L von der Lohe; H Lauer; T Hirsch; A Daigeler; M Lehnhardt; J Kolbenschlag
Journal:  Burns       Date:  2014-06-21       Impact factor: 2.744

6.  A controlled trial of a prostacyclin and rt-PA in the treatment of severe frostbite.

Authors:  Emmanuel Cauchy; Benoit Cheguillaume; Eric Chetaille
Journal:  N Engl J Med       Date:  2011-01-13       Impact factor: 91.245

7.  The effect of body temperature on the hunting response of the middle finger skin temperature.

Authors:  H A Daanen; F J Van de Linde; T T Romet; M B Ducharme
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1997

8.  Reduction of the incidence of amputation in frostbite injury with thrombolytic therapy.

Authors:  Kevin J Bruen; James R Ballard; Stephen E Morris; Amalia Cochran; Linda S Edelman; Jeffrey R Saffle
Journal:  Arch Surg       Date:  2007-06

9.  Early sympathetic blockade for frostbite--is it of value?

Authors:  D L Bouwman; S Morrison; C E Lucas; A M Ledgerwood
Journal:  J Trauma       Date:  1980-09

Review 10.  Frostbite of both first digits of the foot treated with delayed hyperbaric oxygen:a case report and review of literature.

Authors:  Tom C P M Kemper; Vincent M de Jong; Helen A Anema; Albert van den Brink; Robert A van Hulst
Journal:  Undersea Hyperb Med       Date:  2014 Jan-Feb       Impact factor: 0.698

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  4 in total

Review 1.  [Physical and chemical emergencies in dermatology].

Authors:  B Malisiewicz; M Meissner; R Kaufmann; E Valesky
Journal:  Hautarzt       Date:  2018-05       Impact factor: 0.751

2.  Effects of repeated exposures to experimental cold pain stimulus on pain perception in healthy young Indian men.

Authors:  D Savitha; Taniya Anto; Tinku Thomas
Journal:  Med J Armed Forces India       Date:  2021-10-07

3.  A new treatment for frostbite sequelae; Botulinum toxin.

Authors:  Arne Johan Norheim; James Mercer; Frauke Musial; Louis de Weerd
Journal:  Int J Circumpolar Health       Date:  2017       Impact factor: 1.228

4.  Cuscuta reflexa Roxb. Expedites the Healing Process in Contact Frostbite.

Authors:  Waseem Hassan; Manal Ali Buabeid; Umme Kalsoom; Sahar Bakht; Imran Akhtar; Furqan Iqbal; El-Shaimaa A Arafa
Journal:  Biomed Res Int       Date:  2020-10-02       Impact factor: 3.411

  4 in total

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