Literature DB >> 26574979

Malignant Small Bowel Tumors: Diagnosis, Management and Prognosis.

Hélder Cardoso1, João Tiago Rodrigues2, Margarida Marques1, Armando Ribeiro1, Filipe Vilas-Boas1, João Santos-Antunes1, Eduardo Rodrigues-Pinto1, Marco Silva1, José Costa Maia3, Guilherme Macedo1.   

Abstract

PURPOSE: Despite being rare entities, the incidence of malignant small bowel tumors seems to be rising. The development of capsule endoscopy and balloon assisted enteroscopy provided an advance in the assessment of small bowel lesions. We aim to describe the clinical and pathological characteristics of patients with small bowel cancer and ascertain what roles these endoscopic techniques currently have.
MATERIAL AND METHODS: A retrospective study of patients diagnosed with small bowel cancer, from January 2010 to October 2014, was performed. The data was submitted to statistical analysis.
RESULTS: Of the 28 diagnosed patients, 54% were female. The mean age at diagnosis was 61 years. Adenocarcinoma was the most frequent tumor (n = 11), followed by sarcoma (n = 6), lymphoma (n = 6) and neuroendocrine tumors (n = 3). The main form of presentation was related to blood loss or intestinal obstruction. By the time of diagnosis, 46% of patients had distant metastasis/ unresectable cancer. Most of the tumors were diagnosed by endoscopic (41%) or imaging techniques (35%). In the first year after diagnosis, 29% of patients died. In multivariate analysis, adenocarcinoma remained an independent factor for worse survival. DISCUSSION: Patients with adenocarcinoma presented at late stages and with unresectable tumors, contributing to a worse outcome. A high degree of clinical suspicion for the diagnosis of small bowel cancer is necessary.
CONCLUSION: The characteristics of the patients were generally consistent with those described in the literature. Capsule endoscopy and balloon assisted enteroscopy are useful in the diagnosis, management and surveillance of small bowel cancer.

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Year:  2015        PMID: 26574979     DOI: 10.20344/amp.6479

Source DB:  PubMed          Journal:  Acta Med Port        ISSN: 0870-399X


  3 in total

1.  Capsule endoscopy in Portugal.

Authors:  Bruno Rosa
Journal:  Ann Transl Med       Date:  2017-05

2.  Prognostic Factors and Survival Time in Patients with Small Bowel Tumors: A Retrospective Observational Study.

Authors:  Shokouh Taghipour Zahir; Zahra Heidarymeybodi; Sogol AleSaeidi
Journal:  Int J Surg Oncol       Date:  2019-05-02

3.  Artificial Intelligence and Device-Assisted Enteroscopy: Automatic Detection of Enteric Protruding Lesions Using a Convolutional Neural Network.

Authors:  Pedro Cardoso; Miguel Mascarenhas Saraiva; João Afonso; Tiago Ribeiro; Patrícia Andrade; João Ferreira; Hélder Cardoso; Guilherme Macedo
Journal:  Clin Transl Gastroenterol       Date:  2022-07-20       Impact factor: 4.396

  3 in total

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