Jai K Das1, Zulfiqar A Bhutta. 1. aDivision of Women and Child Health, Aga Khan University, Karachi, Pakistan bCentre for Global Child Health, The Hospital for Sick Children, Toronto, Canada.
Abstract
PURPOSE OF REVIEW: Childhood diarrhea is the most common cause of morbidity and mortality, especially in the low and middle-income countries. The burden of child mortality because of diarrhea has declined, but still a lot is desired not only to reduce diarrhea-specific mortality but reduce the overall incidence, and hence the morbidity associated with childhood diarrhea. RECENT FINDINGS: A recent Lancet series on diarrhea suggests that amplification of the current interventions can eliminate virtually all preventable diarrhea deaths. A refocused attention and strategy and collective effort from the multilateral entities to promote water sanitation and hygiene, rotavirus vaccination, nutrition, and improved case management can bridge gaps and tackle the existing undue burden of deaths because of diarrhea. SUMMARY: Investment toward preventing and controlling childhood diarrhea should be a priority, especially when the existing solution is plausible for implementation at scale and in underprivileged settings.
PURPOSE OF REVIEW: Childhood diarrhea is the most common cause of morbidity and mortality, especially in the low and middle-income countries. The burden of child mortality because of diarrhea has declined, but still a lot is desired not only to reduce diarrhea-specific mortality but reduce the overall incidence, and hence the morbidity associated with childhood diarrhea. RECENT FINDINGS: A recent Lancet series on diarrhea suggests that amplification of the current interventions can eliminate virtually all preventable diarrhea deaths. A refocused attention and strategy and collective effort from the multilateral entities to promote water sanitation and hygiene, rotavirus vaccination, nutrition, and improved case management can bridge gaps and tackle the existing undue burden of deaths because of diarrhea. SUMMARY: Investment toward preventing and controlling childhood diarrhea should be a priority, especially when the existing solution is plausible for implementation at scale and in underprivileged settings.
Authors: Salum Mshamu; Arnold Mmbando; Judith Meta; John Bradley; Thomas Chevalier Bøjstrup; Nicholas P J Day; Mavuto Mukaka; Fredros Okumu; Ally Olotu; Christopher Pell; Jacqueline Deen; Jakob Knudsen; Steven W Lindsay; Lorenz von Seidlein Journal: Trials Date: 2022-06-20 Impact factor: 2.728
Authors: Prashant Kumar; Ravi S Shukla; Ashaben Patel; Swathi R Pullagurla; Christopher Bird; Oluwadara Ogun; Ozan S Kumru; Ahd Hamidi; Femke Hoeksema; Christopher Yallop; Julie E Bines; Sangeeta B Joshi; David B Volkin Journal: Hum Vaccin Immunother Date: 2021-04-16 Impact factor: 3.452
Authors: Julie E Bines; Jarir At Thobari; Cahya Dewi Satria; Amanda Handley; Emma Watts; Daniel Cowley; Hera Nirwati; James Ackland; Jane Standish; Frances Justice; Gabrielle Byars; Katherine J Lee; Graeme L Barnes; Novilia S Bachtiar; Ajeng Viska Icanervilia; Karen Boniface; Nada Bogdanovic-Sakran; Daniel Pavlic; Ruth F Bishop; Carl D Kirkwood; Jim P Buttery; Yati Soenarto Journal: N Engl J Med Date: 2018-02-22 Impact factor: 91.245