Literature DB >> 26572079

Multifunctional Silica Nanoparticles for Covalent Immobilization of Highly Sensitive Proteins.

Xu-Dong Wang1, Kersten S Rabe1, Ishtiaq Ahmed1, Christof M Niemeyer1.   

Abstract

A convenient reverse micellar one-pot reaction yields multifunctional silica nanoparticles, which can be tailored to effectively suppress non-specific adsorption and, at the same time, enable efficient specific covalent immobilization of proteins. Using two highly sensitive proteins, it is demonstrated that the new particles provide a suitable microenvironment to maintain the protein's activity.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biomolecules; immobilization; proteins; silica nanoparticles; surface chemistry

Mesh：

Substances：

Year:  2015        PMID： 26572079     DOI： 10.1002/adma.201503935

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  8 in total

1.  Protection of opening lids: very high catalytic activity of lipase immobilized on core-shell nanoparticles.

Authors:  Xuefei Sun; Weipu Zhu; Krzysztof Matyjaszewski
Journal:  Macromolecules       Date:  2018-01-01       Impact factor: 5.985

2.  Stable Immobilization of Enzymes in a Macro- and Mesoporous Silica Monolith.

Authors:  Chengmin Hou; Nicolas Ghéczy; Daniel Messmer; Katarzyna Szymańska; Jozef Adamcik; Raffaele Mezzenga; Andrzej B Jarzębski; Peter Walde
Journal:  ACS Omega       Date:  2019-04-29

3.  Controllable Enzyme Immobilization via Simple and Quantitative Adsorption of Dendronized Polymer-Enzyme Conjugates Inside a Silica Monolith for Enzymatic Flow-Through Reactor Applications.

Authors:  Nicolas Ghéczy; Weina Xu; Katarzyna Szymańska; Andrzej B Jarzębski; Peter Walde
Journal:  ACS Omega       Date:  2022-07-21

4.  A reverse micelle strategy for fabricating magnetic lipase-immobilized nanoparticles with robust enzymatic activity.

Authors:  Shixiong Yi; Fangyin Dai; Cunyi Zhao; Yang Si
Journal:  Sci Rep       Date:  2017-08-29       Impact factor: 4.379

5.  Segregation of Dispersed Silica Nanoparticles in Microfluidic Water-in-Oil Droplets: A Kinetic Study.

Authors:  Sahana Sheshachala; Maximilian Grösche; Tim Scherr; Yong Hu; Pengchao Sun; Andreas Bartschat; Ralf Mikut; Christof M Niemeyer
Journal:  Chemphyschem       Date:  2020-04-09       Impact factor: 3.102

6.  A tailor-made, self-sufficient and recyclable monooxygenase catalyst based on coimmobilized cytochrome P450 BM3 and glucose dehydrogenase.

Authors:  Donya Valikhani; Juan M Bolivar; Alexander Dennig; Bernd Nidetzky
Journal:  Biotechnol Bioeng       Date:  2018-08-29       Impact factor: 4.530

7.  Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings.

Authors:  Yong Hu; Carmen M Domínguez; Jens Bauer; Simone Weigel; Alessa Schipperges; Claude Oelschlaeger; Norbert Willenbacher; Stephan Keppler; Martin Bastmeyer; Stefan Heißler; Christof Wöll; Tim Scharnweber; Kersten S Rabe; Christof M Niemeyer
Journal:  Nat Commun       Date:  2019-12-04       Impact factor: 14.919

8.  Bottom-Up Assembly of DNA-Silica Nanocomposites into Micrometer-Sized Hollow Spheres.

Authors:  Yong Hu; Maximilian Grösche; Sahana Sheshachala; Claude Oelschlaeger; Norbert Willenbacher; Kersten S Rabe; Christof M Niemeyer
Journal:  Angew Chem Int Ed Engl       Date:  2019-10-18       Impact factor: 15.336
  8 in total

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