Literature DB >> 26571336

Oxidation of NADH and ROS production by respiratory complex I.

Andrei D Vinogradov1, Vera G Grivennikova2.   

Abstract

Kinetic characteristics of the proton-pumping NADH:quinone reductases (respiratory complexes I) are reviewed. Unsolved problems of the redox-linked proton translocation activities are outlined. The parameters of complex I-mediated superoxide/hydrogen peroxide generation are summarized, and the physiological significance of mitochondrial ROS production is discussed. This article is part of a Special Issue entitled Respiratory complex I, edited by Volker Zickermann and Ulrich Brandt.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Bacterial plasma membranes; Hydrogen peroxide; Mitochondria; NADH:quinone oxidoreductase; Proton pumping; Superoxide

Mesh：

Substances：

Year:  2015        PMID： 26571336     DOI： 10.1016/j.bbabio.2015.11.004

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  40 in total

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