Literature DB >> 2657103

N myristylation of the human immunodeficiency virus type 1 gag polyprotein precursor in Saccharomyces cerevisiae.

I C Bathurst1, N Chester, H L Gibson, A F Dennis, K S Steimer, P J Barr.   

Abstract

A semisynthetic gene precisely encoding the 502 amino acids of the human immunodeficiency virus type 1 gag precursor (Pr53gag) was expressed in the yeast Saccharomyces cerevisiae. Amino acid sequence analysis of the recombinant Pr53gag showed that the amino terminus was fully blocked. Labeling of Pr53gag with [3H]myristic acid demonstrated that, as with Pr53gag isolated from virus-infected cells, the yeast-derived protein was demethionylated and N myristylated on glycine, the second amino acid residue.

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Year:  1989        PMID： 2657103      PMCID： PMC250878     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  33 in total

1.  Capsid protein VP4 of poliovirus is N-myristoylated.

Authors:  A V Paul; A Schultz; S E Pincus; S Oroszlan; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

2.  Myristoylation and the post-translational acquisition of hydrophobicity by the membrane immunoglobulin heavy-chain polypeptide in B lymphocytes.

Authors:  S Pillai; D Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

3.  Characterization of ribosomal frameshifting in HIV-1 gag-pol expression.

Authors:  T Jacks; M D Power; F R Masiarz; P A Luciw; P J Barr; H E Varmus
Journal:  Nature       Date:  1988-01-21       Impact factor: 49.962

Review 4.  The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

Authors:  A S Fauci
Journal:  Science       Date:  1988-02-05       Impact factor: 47.728

5.  Chemical and immunological characterization of the 21-kDa ADP-ribosylation factor of adenylate cyclase.

Authors:  R A Kahn; C Goddard; M Newkirk
Journal:  J Biol Chem       Date:  1988-06-15       Impact factor: 5.157

6.  Epidemiology of HIV infection and AIDS in the United States.

Authors:  J W Curran; H W Jaffe; A M Hardy; W M Morgan; R M Selik; T J Dondero
Journal:  Science       Date:  1988-02-05       Impact factor: 47.728

7.  A nucleotide substitution in the gag N terminus of the endogenous ecotropic DBA/2 virus prevents Pr65gag myristylation and virus replication.

Authors:  E C Jørgensen; N O Kjeldgaard; F S Pedersen; P Jørgensen
Journal:  J Virol       Date:  1988-09       Impact factor: 5.103

Review 8.  AIDS: an international perspective.

Authors:  P Piot; F A Plummer; F S Mhalu; J L Lamboray; J Chin; J M Mann
Journal:  Science       Date:  1988-02-05       Impact factor: 47.728

9.  Simian retrovirus-D serotype 1 (SRV-1) envelope glycoproteins gp70 and gp20: expression in yeast cells and identification of specific antibodies in sera from monkeys that recovered from SRV-1 infection.

Authors:  H S Kwang; P J Barr; E A Sabin; S Sujipto; P A Marx; M D Power; I C Bathurst; N C Pedersen
Journal:  J Virol       Date:  1988-05       Impact factor: 5.103

10.  Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24.

Authors:  F D Veronese; T D Copeland; S Oroszlan; R C Gallo; M G Sarngadharan
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103
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  8 in total

1.  Incorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell line.

Authors:  M L Bryant; L Ratner; R J Duronio; N S Kishore; B Devadas; S P Adams; J I Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

2.  Vaccinia virus recombinants expressing chimeric proteins of human immunodeficiency virus and gamma interferon are attenuated for nude mice.

Authors:  L D Giavedoni; L Jones; M B Gardner; H L Gibson; C T Ng; P J Barr; T Yilma
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

3.  Human immunodeficiency virus-like, nonreplicating, gag-env particles assemble in a recombinant vaccinia virus expression system.

Authors:  O Haffar; J Garrigues; B Travis; P Moran; J Zarling; S L Hu
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

4.  Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation.

Authors:  Y Li; H Hui; C J Burgess; R W Price; P M Sharp; B H Hahn; G M Shaw
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

5.  HIV type 1 Gag virus-like particle budding from spheroplasts of Saccharomyces cerevisiae.

Authors:  Sayuri Sakuragi; Toshiyuki Goto; Kouichi Sano; Yuko Morikawa
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-11       Impact factor: 11.205

6.  Fatty acids on the A/Japan/305/57 influenza virus hemagglutinin have a role in membrane fusion.

Authors:  C W Naeve; D Williams
Journal:  EMBO J       Date:  1990-12       Impact factor: 11.598

7.  HIV-1 Gag release from yeast reveals ESCRT interaction with the Gag N-terminal protein region.

Authors:  Birgit Meusser; Bettina Purfuerst; Friedrich C Luft
Journal:  J Biol Chem       Date:  2020-09-28       Impact factor: 5.157

8.  ESCRT-independent budding of HIV-1 gag virus-like particles from Saccharomyces cerevisiae spheroplasts.

Authors:  Andrew P Norgan; Jacqueline R E Lee; Andrea J Oestreich; Johanna A Payne; Eugene W Krueger; David J Katzmann
Journal:  PLoS One       Date:  2012-12-21       Impact factor: 3.240
  8 in total

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