Arne Sandmann1, Michael Amling1, Florian Barvencik1, Hans-Helmut König2, Florian Bleibler2. 1. 1Department of Osteology and Biomechanics,University Medical Center Hamburg-Eppendorf,Martinistraße 52,D-20246 Hamburg,Germany. 2. 2Department of Health Economics and Health Services Research,Hamburg Center for Health Economics,University Medical Center Hamburg-Eppendorf,Hamburg,Germany.
Abstract
OBJECTIVE: The study evaluates the economic benefit of population-wide vitamin D and Ca food fortification in Germany. DESIGN: Based on a spreadsheet model, we compared the cost of a population-wide vitamin D and Ca food-fortification programme with the potential cost savings from prevented fractures in the German female population aged 65 years and older. SETTING: The annual burden of disease and the intervention cost were assessed for two scenarios: (i) no food fortification; and (ii) voluntary food fortification with 20 µg (800 IU) of cholecalciferol (vitamin D3) and 200 mg of Ca. The analysis considered six types of fractures: hip, clinical vertebral, humerus, wrist, other femur and pelvis. SUBJECTS: Subgroups of the German population defined by age and sex. RESULTS: The implementation of a vitamin D and Ca food-fortification programme in Germany would lead to annual net cost savings of €315 million and prevention of 36 705 fractures in the target population. CONCLUSIONS: Vitamin D and Ca food fortification is an economically beneficial preventive health strategy that has the potential to reduce the future health burden of osteoporotic fractures in Germany. The implementation of a vitamin D and Ca food-fortification programme should be a high priority for German health policy makers because it offers substantial cost-saving potential for the German health and social care systems.
OBJECTIVE: The study evaluates the economic benefit of population-wide vitamin D and Ca food fortification in Germany. DESIGN: Based on a spreadsheet model, we compared the cost of a population-wide vitamin D and Ca food-fortification programme with the potential cost savings from prevented fractures in the German female population aged 65 years and older. SETTING: The annual burden of disease and the intervention cost were assessed for two scenarios: (i) no food fortification; and (ii) voluntary food fortification with 20 µg (800 IU) of cholecalciferol (vitamin D3) and 200 mg of Ca. The analysis considered six types of fractures: hip, clinical vertebral, humerus, wrist, other femur and pelvis. SUBJECTS: Subgroups of the German population defined by age and sex. RESULTS: The implementation of a vitamin D and Ca food-fortification programme in Germany would lead to annual net cost savings of €315 million and prevention of 36 705 fractures in the target population. CONCLUSIONS:Vitamin D and Ca food fortification is an economically beneficial preventive health strategy that has the potential to reduce the future health burden of osteoporotic fractures in Germany. The implementation of a vitamin D and Ca food-fortification programme should be a high priority for German health policy makers because it offers substantial cost-saving potential for the German health and social care systems.
Authors: Gabriela Cormick; Ana Pilar Betrán; Fletcher Metz; Cristina Palacios; Filiberto Beltrán-Velazquez; María de Las Nieves García-Casal; Juan Pablo Peña-Rosas; G Justus Hofmeyr; José M Belizán Journal: Nutrients Date: 2020-04-08 Impact factor: 5.717
Authors: Stefan Pilz; Winfried März; Kevin D Cashman; Mairead E Kiely; Susan J Whiting; Michael F Holick; William B Grant; Pawel Pludowski; Mickael Hiligsmann; Christian Trummer; Verena Schwetz; Elisabeth Lerchbaum; Marlene Pandis; Andreas Tomaschitz; Martin R Grübler; Martin Gaksch; Nicolas Verheyen; Bruce W Hollis; Lars Rejnmark; Spyridon N Karras; Andreas Hahn; Heike A Bischoff-Ferrari; Jörg Reichrath; Rolf Jorde; Ibrahim Elmadfa; Reinhold Vieth; Robert Scragg; Mona S Calvo; Natasja M van Schoor; Roger Bouillon; Paul Lips; Suvi T Itkonen; Adrian R Martineau; Christel Lamberg-Allardt; Armin Zittermann Journal: Front Endocrinol (Lausanne) Date: 2018-07-17 Impact factor: 5.555