Emily Kline1, Elizabeth Thompson1, Caroline Demro1, Kristin Bussell1, Gloria Reeves1, Jason Schiffman1. 1. Dr. Kline is with the Department of Psychiatry, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston (e-mail: ekline@bidmc.harvard.edu ). Ms. Thompson, Ms. Demro, and Dr. Schiffman are with the Department of Psychology, University of Maryland, Baltimore County, Baltimore. Ms. Bussell and Dr. Reeves are with the Department of Psychiatry, University of Maryland Medical School, Baltimore.
Abstract
OBJECTIVE: Practice guidelines emphasize frequent clinical monitoring of patients at high risk for psychosis. No brief instrument assessing attenuated psychotic symptoms has been validated for this purpose. This study examined use of three self-report questionnaires, which were developed as psychosis risk screeners, for monitoring symptom severity in a naturalistic clinical sample of 54 adolescents. METHODS: Self-report measures (Prime Screen-Revised, Prodromal Questionnaire-Brief Version [PQ-B], and Youth Psychosis At-Risk Questionnaire-Brief) and clinician assessments (Structured Interview for Psychosis Risk Syndromes) were administered to participants at baseline and six months. RESULTS: Changes in self-report scores were moderately correlated with changes in clinician ratings. The PQ-B demonstrated slightly better agreement with changes in clinician ratings than the other two measures. CONCLUSIONS: Questionnaires developed as psychosis risk screeners could be used for symptom monitoring. Further validation of tools to monitor attenuated symptoms will be a valuable step toward developing an evidence-based approach for treating high-risk youths.
OBJECTIVE: Practice guidelines emphasize frequent clinical monitoring of patients at high risk for psychosis. No brief instrument assessing attenuated psychotic symptoms has been validated for this purpose. This study examined use of three self-report questionnaires, which were developed as psychosis risk screeners, for monitoring symptom severity in a naturalistic clinical sample of 54 adolescents. METHODS: Self-report measures (Prime Screen-Revised, Prodromal Questionnaire-Brief Version [PQ-B], and Youth Psychosis At-Risk Questionnaire-Brief) and clinician assessments (Structured Interview for Psychosis Risk Syndromes) were administered to participants at baseline and six months. RESULTS: Changes in self-report scores were moderately correlated with changes in clinician ratings. The PQ-B demonstrated slightly better agreement with changes in clinician ratings than the other two measures. CONCLUSIONS: Questionnaires developed as psychosis risk screeners could be used for symptom monitoring. Further validation of tools to monitor attenuated symptoms will be a valuable step toward developing an evidence-based approach for treating high-risk youths.
Authors: Elizabeth C Thompson; Anthony Spirito; Jiayin Sperry Saarinen; Jennifer C Wolff Journal: Early Interv Psychiatry Date: 2020-09-21 Impact factor: 2.721
Authors: Gonzalo Salazar de Pablo; Livia Soardo; Anna Cabras; Joana Pereira; Simi Kaur; Filippo Besana; Vincenzo Arienti; Francesco Coronelli; Jae Il Shin; Marco Solmi; Natalia Petros; Andre F Carvalho; Philip McGuire; Paolo Fusar-Poli Journal: Epidemiol Psychiatr Sci Date: 2022-01-19 Impact factor: 6.892