Literature DB >> 26567892

A Near-Infrared Laser-Activated "Nanobomb" for Breaking the Barriers to MicroRNA Delivery.

Hai Wang1,2,3, Pranay Agarwal1,2, Shuting Zhao1,2, Jianhua Yu3,4, Xiongbin Lu5, Xiaoming He1,2,3.   

Abstract

A near-infrared laser-activated "nanobomb" is synthesized using lipid and multiple polymers to break the extra-cellular and intracellular barriers to cytosolic delivery of microRNAs. The nanobomb can be used to effectively destroy tumors and cancer stem-like cells in vitro and in vivo with minimal side effects.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  cancer stem-like cells; endosomal escape; gene delivery; microRNAs; nanoparticles

Mesh：

Substances：

Year:  2015        PMID： 26567892     DOI： 10.1002/adma.201504263

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  17 in total

Review 1.  Smart Nanostructures for Cargo Delivery: Uncaging and Activating by Light.

Authors:  Mahdi Karimi; Parham Sahandi Zangabad; Soodeh Baghaee-Ravari; Mehdi Ghazadeh; Hamid Mirshekari; Michael R Hamblin
Journal:  J Am Chem Soc       Date:  2017-03-13       Impact factor: 15.419

2.  Combined cancer therapy with hyaluronan-decorated fullerene-silica multifunctional nanoparticles to target cancer stem-like cells.

Authors:  Hai Wang; Pranay Agarwal; Shuting Zhao; Jianhua Yu; Xiongbin Lu; Xiaoming He
Journal:  Biomaterials       Date:  2016-04-26       Impact factor: 12.479

Review 3.  Biomaterials-Based Approaches to Tumor Spheroid and Organoid Modeling.

Authors:  Pradip Shahi Thakuri; Chun Liu; Gary D Luker; Hossein Tavana
Journal:  Adv Healthc Mater       Date:  2017-12-04       Impact factor: 9.933

4.  Enhanced cancer therapy with cold-controlled drug release and photothermal warming enabled by one nanoplatform.

Authors:  Hai Wang; Pranay Agarwal; Yutong Liang; Jiangsheng Xu; Gang Zhao; Katherine H R Tkaczuk; Xiongbin Lu; Xiaoming He
Journal:  Biomaterials       Date:  2018-07-17       Impact factor: 12.479

5.  Dendrimer-Based Platform for Effective Capture of Tumor Cells after TGFβ1-Induced Epithelial-Mesenchymal Transition.

Authors:  Ja Hye Myung; Ashley Cha; Kevin A Tam; Michael Poellmann; Alain Borgeat; Roohollah Sharifi; Robert E Molokie; Gina Votta-Velis; Seungpyo Hong
Journal:  Anal Chem       Date:  2019-06-19       Impact factor: 6.986

6.  Metformin Bicarbonate-Mediated Efficient RNAi for Precise Targeting of TP53 Deficiency in Colon and Rectal Cancers.

Authors:  Jiangsheng Xu; Yunhua Liu; Sheng Liu; Wenquan Ou; Alisa White; Samantha Stewart; Katherine H R Tkaczuk; Lee M Ellis; Jun Wan; Xiongbin Lu; Xiaoming He
Journal:  Nano Today       Date:  2022-02-01       Impact factor: 20.722

7.  Targeted Heating of Mitochondria Greatly Augments Nanoparticle-Mediated Cancer Chemotherapy.

Authors:  Jiangsheng Xu; James G Shamul; Hai Wang; John Lin; Pranay Agarwal; Mingrui Sun; Xiongbin Lu; Katherine H R Tkaczuk; Xiaoming He
Journal:  Adv Healthc Mater       Date:  2020-06-17       Impact factor: 9.933

8.  Photoresponsive miR-34a/Nanoshell Conjugates Enable Light-Triggered Gene Regulation to Impair the Function of Triple-Negative Breast Cancer Cells.

Authors:  Megan N Dang; Carolina Gomez Casas; Emily S Day
Journal:  Nano Lett       Date:  2020-12-11       Impact factor: 11.189

9.  Parallel comparative studies on toxicity of quantum dots synthesized and surface engineered with different methods in vitro and in vivo.

Authors:  Fengjun Liu; Wen Ye; Jun Wang; Fengxiang Song; Yingsheng Cheng; Bingbo Zhang
Journal:  Int J Nanomedicine       Date:  2017-07-19

10.  A Nano-In-Micro System for Enhanced Stem Cell Therapy of Ischemic Diseases.

Authors:  Hai Wang; Pranay Agarwal; Yichao Xiao; Hao Peng; Shuting Zhao; Xuanyou Liu; Shenghua Zhou; Jianrong Li; Zhenguo Liu; Xiaoming He
Journal:  ACS Cent Sci       Date:  2017-07-19       Impact factor: 14.553
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