Literature DB >> 2656470

Corticotropin-releasing hormone: from endocrinology to psychobiology.

M A Smith1, M A Kling, H J Whitfield, H A Brandt, M A Demitrack, T D Geracioti, G P Chrousos, P W Gold.   

Abstract

Corticotropin-releasing hormone (CRH) is a brain neuropeptide which coordinates the endocrine, autonomic and behavioral responses to stress. We review the abnormal response to exogenous CRH in various psychiatric syndromes, including major depression and anorexia nervosa. We also contrast pituitary responses to CRH in patients with depression versus Cushing's disease. We hypothesize that CRH may play a role in the pathogenesis of various psychiatric syndromes which are characterized during their course by the symptom of depression.

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Year:  1989        PMID： 2656470     DOI： 10.1159/000181089

Source DB:  PubMed          Journal:  Horm Res        ISSN： 0301-0163


  5 in total

1.  Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates.

Authors:  K E Habib; K P Weld; K C Rice; J Pushkas; M Champoux; S Listwak; E L Webster; A J Atkinson; J Schulkin; C Contoreggi; G P Chrousos; S M McCann; S J Suomi; J D Higley; P W Gold
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  The inhibitory effect of hormones associated with stress on Na appetite of sheep.

Authors:  R S Weisinger; J R Blair-West; P Burns; D A Denton; M J McKinley; B Purcell; W Vale; J Rivier; K Sunagawa
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

3.  Alpha 2- and beta-adrenergic stimulation of corticosterone secretion in rats.

Authors:  W M Daniels; A Jaffer; V A Russell; J J Taljaard
Journal:  Neurochem Res       Date:  1993-02       Impact factor: 3.996

Review 4.  Circadian endocrine rhythms: the hypothalamic-pituitary-adrenal axis and its actions.

Authors:  Nicolas C Nicolaides; Evangelia Charmandari; George P Chrousos; Tomoshige Kino
Journal:  Ann N Y Acad Sci       Date:  2014-05       Impact factor: 5.691

5.  Sex differences in corticotropin-releasing factor receptor signaling and trafficking: potential role in female vulnerability to stress-related psychopathology.

Authors:  D A Bangasser; A Curtis; B A S Reyes; T T Bethea; I Parastatidis; H Ischiropoulos; E J Van Bockstaele; R J Valentino
Journal:  Mol Psychiatry       Date:  2010-06-15       Impact factor: 15.992
  5 in total

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