Literature DB >> 26564121

Portal hypertensive gastropathy and gastric antral vascular ectasia.

Hitendra Garg1, Subhash Gupta2, A C Anand2, S L Broor2,3.   

Abstract

Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are gastric mucosal lesions that mostly present as chronic anemia and rarely cause the acute gastrointestinal hemorrhage. Despite similar clinical manifestations, their pathophysiology and management are entirely different. PHG is seen exclusively in patients with portal hypertension, but GAVE can also be observed in patients with other conditions. Their diagnosis is endoscopic, and although generally each of them has a characteristic endoscopic appearance and distribution, there are cases in which the differential is difficult and must rely on histology. This review focuses on the management of both entities. The mainstay of management of PHG is based on portal-hypotensive pharmacological treatment while GAVE benefits from hormonal therapy, endoscopic Nd:YAG laser, and argon plasma coagulation. More invasive options should be reserved for refractory cases.

Entities:  

Keywords:  Argon plasma coagulation; Liver disease; Portal hypertension

Mesh：

Substances：

Year:  2015        PMID： 26564121     DOI： 10.1007/s12664-015-0605-0

Source DB:  PubMed          Journal:  Indian J Gastroenterol        ISSN： 0254-8860


  76 in total

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Journal:  J Clin Gastroenterol       Date:  2002-03       Impact factor: 3.062

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4.  Two cases of gastric antral vascular ectasia--response to medical treatment.

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Journal:  Gut       Date:  1991-01       Impact factor: 23.059

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Journal:  J Gastroenterol Hepatol       Date:  1996-09       Impact factor: 4.029

7.  Treatment of chronic bleeding from gastric antral vascular ectasia (GAVE) with estrogen-progesterone in cirrhotic patients: an open pilot study.

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Journal:  Am J Gastroenterol       Date:  1999-10       Impact factor: 10.864

8.  Cure of gastric antral vascular ectasia by liver transplantation despite persistent portal hypertension: a clue for pathogenesis.

Authors:  Catherine Vincent; Gilles Pomier-Layrargues; Michel Dagenais; Réal Lapointe; Richard Létourneau; André Roy; Pierre Paré; P Michel Huet
Journal:  Liver Transpl       Date:  2002-08       Impact factor: 5.799

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Journal:  Gastroenterology       Date:  1992-03       Impact factor: 22.682

10.  Treatment of gastric antral vascular ectasia (watermelon stomach) with endoscopic band ligation.

Authors:  Christopher D Wells; M Edwyn Harrison; Suryakanth R Gurudu; Michael D Crowell; Thomas J Byrne; Giovanni Depetris; Virender K Sharma
Journal:  Gastrointest Endosc       Date:  2008-06-03       Impact factor: 9.427
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  3 in total

1.  A Two-Month-Old Child with Vascular Ectasia: A Case Report Diagnosed by Molecular Karyotyping.

Authors:  Ozlem Tolu Kendir; Hayri Levent Yilmaz; Sevcan Bozdogan; Atıl Bisgin; Tugçe Celik; Ozgur Surmelioglu; Figen Doran
Journal:  J Pediatr Genet       Date:  2018-08-22

2.  Gastric antral vascular ectasia is more frequent in patients with non-alcoholic steatohepatitis-induced cirrhosis.

Authors:  Aline Le Cleac'h; Jean-Pierre Villeneuve; Marie-Pierre Sylvestre; Geneviève Huard; Jeanne-Marie Giard; Saskia Ditisheim
Journal:  Can Liver J       Date:  2019-08-27

3.  IL-6-driven FasL promotes NF-κBp65/PUMA-mediated apoptosis in portal hypertensive gastropathy.

Authors:  Siwei Tan; Minyi Xu; Bilun Ke; Yu Lu; Huiling Liu; Jie Jiang; Bin Wu
Journal:  Cell Death Dis       Date:  2019-10-03       Impact factor: 8.469
  3 in total

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