Literature DB >> 26563428

Smart materials: in situ gel-forming systems for nasal delivery.

Christina Karavasili1, Dimitrios G Fatouros2.   

Abstract

In the last decade in situ gelling systems have emerged as a novel approach in intranasal delivery of therapeutics, capturing the interest of scientific community. Considerable advances have been currently made in the development of novel formulations containing both natural and synthetic polymers. In this paper we present recent developments on in situ gelling systems for nasal delivery, highlighting the mechanisms that govern their formation.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 26563428     DOI： 10.1016/j.drudis.2015.10.016

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  16 in total

1.  In vitro and ex vivo characterisation of an in situ gelling formulation for sustained lidocaine release with potential use following knee arthroplasty.

Authors:  Manisha Sharma; Kaushik Chandramouli; Louise Curley; Beau Pontre; Keryn Reilly; Jacob Munro; Andrew Hill; Simon Young; Darren Svirskis
Journal:  Drug Deliv Transl Res       Date:  2018-06       Impact factor: 4.617

2.  Nose-to-Brain Delivery by Nanosuspensions-Based in situ Gel for Breviscapine.

Authors:  Yingchong Chen; Yuling Liu; Jin Xie; Qin Zheng; Pengfei Yue; Liru Chen; Pengyi Hu; Ming Yang
Journal:  Int J Nanomedicine       Date:  2020-12-23

3.  Drug-Loaded Supramolecular Gels Prepared in a Microfluidic Platform: Distinctive Rheology and Delivery through Controlled Far-from-Equilibrium Mixing.

Authors:  Gowtham Sathyanarayanan; Mafalda Rodrigues; David Limón; Romén Rodriguez-Trujillo; Josep Puigmartí-Luis; Lluïsa Pérez-García; David B Amabilino
Journal:  ACS Omega       Date:  2017-12-12

Review 4.  New Opportunity to Formulate Intranasal Vaccines and Drug Delivery Systems Based on Chitosan.

Authors:  Roxana Popescu; Mihaela Violeta Ghica; Cristina-Elena Dinu-Pîrvu; Valentina Anuța; Dumitru Lupuliasa; Lăcrămioara Popa
Journal:  Int J Mol Sci       Date:  2020-07-16       Impact factor: 5.923

Review 5.  Mucosal Applications of Poloxamer 407-Based Hydrogels: An Overview.

Authors:  Elena Giuliano; Donatella Paolino; Massimo Fresta; Donato Cosco
Journal:  Pharmaceutics       Date:  2018-09-12       Impact factor: 6.321

Review 6.  Natural Polysaccharide Carriers in Brain Delivery: Challenge and Perspective.

Authors:  Manuela Curcio; Giuseppe Cirillo; Jourdin R C Rouaen; Federica Saletta; Fiore Pasquale Nicoletta; Orazio Vittorio; Francesca Iemma
Journal:  Pharmaceutics       Date:  2020-12-06       Impact factor: 6.321

7.  Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer.

Authors:  Dinghu Zhang; Yanhong Chu; Hanqing Qian; Lingyu Qian; Jie Shao; Qiuping Xu; Lixia Yu; Rutian Li; Quanan Zhang; Fenglei Wu; Baorui Liu; Qin Liu
Journal:  Int J Nanomedicine       Date:  2020-01-31

8.  A mucoadhesive, thermoreversible in situ nasal gel of geniposide for neurodegenerative diseases.

Authors:  Yingting Wang; Shulong Jiang; Hongli Wang; Haiyan Bie
Journal:  PLoS One       Date:  2017-12-14       Impact factor: 3.240

Review 9.  Biopolymer-based strategies in the design of smart medical devices and artificial organs.

Authors:  Lina Altomare; Lorenzo Bonetti; Chiara E Campiglio; Luigi De Nardo; Lorenza Draghi; Francesca Tana; Silvia Farè
Journal:  Int J Artif Organs       Date:  2018-04-03       Impact factor: 1.595

Review 10.  Recent Advances in the Development of In Situ Gelling Drug Delivery Systems for Non-Parenteral Administration Routes.

Authors:  Barbara Vigani; Silvia Rossi; Giuseppina Sandri; Maria Cristina Bonferoni; Carla M Caramella; Franca Ferrari
Journal:  Pharmaceutics       Date:  2020-09-10       Impact factor: 6.321
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