| Literature DB >> 26562288 |
Emily A Seidler1, Kelle H Moley1.
Abstract
Mitochondrial production of cellular energy is essential to oocyte function, zygote development and successful continuation of pregnancy. This review focuses on several key functions of healthy oocyte mitochondria and the effect of pathologic states such as aging, oxidative stress and apoptosis on these functions. The effect of these abnormal conditions is presented in terms of clinical presentations, specifically maternal obesity, diminished ovarian reserve and assisted reproductive technologies. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Entities:
Mesh:
Substances:
Year: 2015 PMID: 26562288 DOI: 10.1055/s-0035-1567822
Source DB: PubMed Journal: Semin Reprod Med ISSN: 1526-4564 Impact factor: 1.303