| Literature DB >> 26561223 |
Robin Cho1, Danielle Ghag2, Mohamud Amirali Karim3, Clifford Lo1.
Abstract
A 74-year-old woman with end-stage renal disease presented with clinical symptoms of encapsulating peritoneal sclerosis 2 years after switching from peritoneal dialysis to haemodialysis. Imaging revealed a large cystic structure in her abdomen and her final diagnosis was made by exploratory laparotomy. A 10 cm×15 cm fibrous rind was excised from the peritoneum and the patient was subsequently started on tamoxifen 20 mg daily and prednisone 20 mg daily. Given her reduction in clinical symptoms and concerns about the long-term effects of corticosteroids, prednisone was tapered and she remained on tamoxifen monotherapy. 1 year postsurgery, she presented with symptoms of nausea, vomiting and anorexia. A repeat CT of the abdomen confirmed a recurrence of encapsulating peritoneal sclerosis. Prednisone and tamoxifen were restarted at increased dosages of 25 and 40 mg daily, respectively. The patient's symptoms were ameliorated within 2 weeks of drug therapy modification. 2015 BMJ Publishing Group Ltd.Entities:
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Year: 2015 PMID： 26561223 PMCID： PMC4654214 DOI： 10.1136/bcr-2015-211490
Source DB: PubMed Journal: BMJ Case Rep ISSN： 1757-790X