| Literature DB >> 26561062 |
Amir Sarrafchi, Mahmoud Bahmani, Hedayatollah Shirzad, Mahmoud Rafieian-Kopaei1.
Abstract
Parkinson's disease (PD) is a neurodegenerative disorder due to dopamine deficit in substatia nigra. PD is mainly a sporadic disease with unestablished etiology. However, exposure to environmental toxins, head trauma, inflammation, and free radicals are potential reasons. Recently, the role of oxidative stress in neurological abnormalities, including PD, has been particularly addressed. Antioxidant remedies, particularly herbal antioxidants, have revealed new perspectives of research and therapy as possible preventive and therapeutic approaches for PD. In this paper, we reviewed the recently published papers on the effects of herbal medicines on PD alongside the pathogenesis of PD with regard to oxidative stress.Entities:
Mesh:
Substances:
Year: 2016 PMID: 26561062 DOI: 10.2174/1381612822666151112151653
Source DB: PubMed Journal: Curr Pharm Des ISSN: 1381-6128 Impact factor: 3.116