| Literature DB >> 26559569 |
Bert Vogelstein1, Kenneth W Kinzler.
Abstract
Focusing on driver-gene mutations and the pathways they control has rendered complex cancer-genome landscapes intelligible. In solid tumors of adults, alterations in as few as three driver genes appear to suffice for a cell to evolve into an advanced cancer.Entities:
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Year: 2015 PMID: 26559569 DOI: 10.1056/NEJMp1508811
Source DB: PubMed Journal: N Engl J Med ISSN: 0028-4793 Impact factor: 91.245