| Literature DB >> 26558188 |
Olga Baraldi1, Chiara Valentini1, Gabriele Donati1, Giorgia Comai1, Vania Cuna1, Irene Capelli1, Maria Laura Angelini1, Maria Ilaria Moretti1, Andrea Angeletti1, Fabio Piscaglia1, Gaetano La Manna1.
Abstract
Acute kidney injury (AKI) is a common complication in patients with end-stage liver disease and advanced cirrhosis regardless of the underlying cause. Hepatorenal syndrome (HRS), a functional form of kidney failure, is one of the many possible causes of AKI. HRS is potentially reversible but involves highly complex pathogenetic mechanisms and equally complex clinical and therapeutic management. Once HRS has developed, it has a very poor prognosis. This review focuses on the diagnostic approach to HRS and discusses the therapeutic protocols currently adopted in clinical practice.Entities:
Keywords: Acute kidney injury; Cirrhosis; Diagnosis; Hepatorenal syndrome; Liver support system; Terlipressin; Treatment
Year: 2015 PMID: 26558188 PMCID: PMC4635371 DOI: 10.5527/wjn.v4.i5.511
Source DB: PubMed Journal: World J Nephrol ISSN: 2220-6124