Literature DB >> 26557953

Hepatocellular adenoma: An update.

Adarsh Vijay1, Ahmed Elaffandi1, Hatem Khalaf1.   

Abstract

Hepatocellular adenomas (HCA) are rare benign liver tumors. Recent technological advancements have helped in the early identification of such lesions. However, precise diagnosis of hepatocellular incidentalomas remains challenging. Studies at the molecular level have provided new insights into the genetics and pathophysiology of these lesions. These in turn have raised questions over their existing management modalities. However, the rarity of the tumor still restricts the quality of evidence available for current recommendations and guidelines. This article provides a comprehensive review on the etiology, molecular biology, patho-physiology, clinical manifestations, and complications associated with HCA. It also elaborates on the genetic advancements, existing diagnostic tools and current guidelines for management for such lesions.

Entities:  

Keywords:  Benign liver lesion; Focal liver lesion; Liver adenoma

Year:  2015        PMID: 26557953      PMCID: PMC4635146          DOI: 10.4254/wjh.v7.i25.2603

Source DB:  PubMed          Journal:  World J Hepatol


  47 in total

Review 1.  Liver adenomatosis: reappraisal, diagnosis, and surgical management: eight new cases and review of the literature.

Authors:  L Chiche; T Dao; E Salamé; M P Galais; N Bouvard; G Schmutz; P Rousselot; P Bioulac-Sage; P Ségol; M Gignoux
Journal:  Ann Surg       Date:  2000-01       Impact factor: 12.969

2.  Management of hepatocellular adenoma during pregnancy.

Authors:  Johanna E Noels; Susanna M van Aalten; Dirk J van der Windt; Niels F M Kok; Rob A de Man; Turkan Terkivatan; Jan N M Ijzermans
Journal:  J Hepatol       Date:  2010-09-22       Impact factor: 25.083

3.  Risk factors for bleeding in hepatocellular adenoma.

Authors:  M Bieze; S S K S Phoa; J Verheij; K P van Lienden; T M van Gulik
Journal:  Br J Surg       Date:  2014-04-24       Impact factor: 6.939

4.  Hepatocellular adenoma subtypes: the impact of overweight and obesity.

Authors:  Paulette Bioulac-Sage; Said Taouji; Laurent Possenti; Charles Balabaud
Journal:  Liver Int       Date:  2012-03-19       Impact factor: 5.828

5.  Diagnostic accuracy of MRI in differentiating hepatocellular adenoma from focal nodular hyperplasia: prospective study of the additional value of gadoxetate disodium.

Authors:  Matthanja Bieze; Jacomina W van den Esschert; C Yung Nio; Joanne Verheij; Johannes B Reitsma; Valeska Terpstra; Thomas M van Gulik; Saffire S K S Phoa
Journal:  AJR Am J Roentgenol       Date:  2012-07       Impact factor: 3.959

6.  Treatment of multiple hepatic adenomatosis using transarterial chemoembolization: a case report.

Authors:  Sang Hoon Lee; Seong Tai Hahn
Journal:  Cardiovasc Intervent Radiol       Date:  2004-06-17       Impact factor: 2.740

7.  Surgical management of benign tumors of the liver.

Authors:  U S Kammula; J F Buell; D M Labow; S Rosen; J M Millis; M C Posner
Journal:  Int J Gastrointest Cancer       Date:  2001

8.  Regression of hepatic adenomas in type Ia glycogen storage disease with dietary therapy.

Authors:  P Parker; I Burr; A Slonim; F K Ghishan; H Greene
Journal:  Gastroenterology       Date:  1981-09       Impact factor: 22.682

Review 9.  Indications for liver transplantation in hepatobiliary malignancy.

Authors:  R Pichlmayr; A Weimann; B Ringe
Journal:  Hepatology       Date:  1994-07       Impact factor: 17.425

Review 10.  Molecular pathogenesis of hepatic adenomas and its implications for surgical management.

Authors:  Siong-Seng Liau; M Saeed Qureshi; Raaj Praseedom; Emmanuel Huguet
Journal:  J Gastrointest Surg       Date:  2013-07-09       Impact factor: 3.452

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  8 in total

1.  Beta-Catenin Staining of Hepatocellular Adenomas.

Authors:  Monica T Garcia-Buitrago
Journal:  Gastroenterol Hepatol (N Y)       Date:  2017-12

2.  Malignant transformation of hepatic adenoma complicated by rupture and hemorrhage: An extremely rare clinical entity.

Authors:  Rishi Philip Mathew; Florin Manolea; Safwat Girgis; Vimal Patel; Gavin Low
Journal:  Intractable Rare Dis Res       Date:  2019-11

Review 3.  Current Approaches in the Management of Hepatic Adenomas.

Authors:  Diamantis I Tsilimigras; Amir A Rahnemai-Azar; Ioannis Ntanasis-Stathopoulos; Maria Gavriatopoulou; Demetrios Moris; Eleftherios Spartalis; Jordan M Cloyd; Sharon M Weber; Timothy M Pawlik
Journal:  J Gastrointest Surg       Date:  2018-08-14       Impact factor: 3.452

4.  18-Fluoro-deoxyglucose uptake in inflammatory hepatic adenoma: A case report.

Authors:  Willy Liu; Jean Delwaide; Noella Bletard; Philippe Delvenne; Paul Meunier; Roland Hustinx; Olivier Detry
Journal:  World J Hepatol       Date:  2017-04-18

5.  Living Donor Liver Transplantation as a Backup Procedure: Treatment Strategy for Hepatocellular Adenomas Requiring Complex Resections.

Authors:  Eduardo A Fonseca; Flavia Feier; Rodrigo Vincenzi; Helry L L Candido; Rodrigo L Azambuja; Fabio Payao; Marcel R Benavides; Karina M O Roda; Katia M R Leite; Cristiane M F Ribeiro; Maria D Begnami; Charles E Zurstrassen; Francisco C Carnevale; Paulo Chapchap; João Seda-Neto
Journal:  Case Rep Surg       Date:  2022-02-17

6.  Prevalence of thoracoabdominal imaging findings in tuberous sclerosis complex.

Authors:  David M Ritter; Bailey K Fessler; Daniel Ebrahimi-Fakhari; Jun Wei; David N Franz; Darcy A Krueger; Andrew T Trout; Alexander J Towbin
Journal:  Orphanet J Rare Dis       Date:  2022-03-15       Impact factor: 4.123

7.  Modeling age-specific incidence of colon cancer via niche competition.

Authors:  Steffen Lange; Richard Mogwitz; Denis Hünniger; Anja Voß-Böhme
Journal:  PLoS Comput Biol       Date:  2022-08-19       Impact factor: 4.779

8.  Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches.

Authors:  Thomas Buder; Andreas Deutsch; Barbara Klink; Anja Voss-Böhme
Journal:  Front Oncol       Date:  2019-01-10       Impact factor: 6.244

  8 in total

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