Literature DB >> 26557952

Dietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future.

Mehran Rahimlou1, Hoda Ahmadnia1, Azita Hekmatdoost1.   

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children. High prevalence of pediatric obesity and sedentary lifestyle has augmented the incidence of NAFLD in children. Obesity is associated with an increased risk of NAFLD through various mechanisms such as intensification of insulin resistance and increased levels of inflammatory markers. There is no approved medical intervention for treatment of pediatric NAFLD; the only proven strategy in management of pediatric NAFLD is lifestyle modification. Recently, the effects of nutritional supplements have been examined in the management of pediatric NAFLD. The purpose of this review is to summarize the studies evaluating the effects of nutritional supplements on pediatric NAFLD and explain the future direction in this field.

Entities:  

Keywords:  Diet; Dietary supplement; Fatty liver; Nutrition; Pediatric non-alcoholic fatty liver disease

Year:  2015        PMID： 26557952      PMCID： PMC4635145          DOI： 10.4254/wjh.v7.i25.2597

Source DB:  PubMed          Journal:  World J Hepatol


  57 in total

1.  Liver fibrosis in overweight patients.

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Journal:  Gastroenterology       Date:  2000-06       Impact factor: 22.682

Review 2.  Is weight reduction an effective therapy for nonalcoholic fatty liver? A systematic review.

Authors:  Rex T Wang; Ronald L Koretz; Hal F Yee
Journal:  Am J Med       Date:  2003-11       Impact factor: 4.965

3.  Synbiotic supplementation in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled pilot study.

Authors:  Tannaz Eslamparast; Hossein Poustchi; Farhad Zamani; Maryam Sharafkhah; Reza Malekzadeh; Azita Hekmatdoost
Journal:  Am J Clin Nutr       Date:  2014-01-08       Impact factor: 7.045

4.  Effects of synbiotic supplementation on insulin resistance in subjects with the metabolic syndrome: a randomised, double-blind, placebo-controlled pilot study.

Authors:  Tannaz Eslamparast; Farhad Zamani; Azita Hekmatdoost; Maryam Sharafkhah; Sareh Eghtesad; Reza Malekzadeh; Hossein Poustchi
Journal:  Br J Nutr       Date:  2014-05-22       Impact factor: 3.718

5.  Docosahexaenoic acid supplementation decreases liver fat content in children with non-alcoholic fatty liver disease: double-blind randomised controlled clinical trial.

Authors:  Valerio Nobili; Giorgio Bedogni; Anna Alisi; Andrea Pietrobattista; Patrizia Risé; Claudio Galli; Carlo Agostoni
Journal:  Arch Dis Child       Date:  2011-01-12       Impact factor: 3.791

6.  Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.

Authors:  Shihui Chen; Xiaolan Zhao; Li Ran; Jing Wan; Xiaofang Wang; Yu Qin; Furong Shu; Yanxiang Gao; Lijia Yuan; Qianyong Zhang; Mantian Mi
Journal:  Dig Liver Dis       Date:  2014-12-16       Impact factor: 4.088

Review 7.  Non-alcoholic fatty liver disease pathogenesis: the present and the future.

Authors:  S Petta; C Muratore; A Craxì
Journal:  Dig Liver Dis       Date:  2009-02-14       Impact factor: 4.088

8.  Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability.

Authors:  P D Cani; S Possemiers; T Van de Wiele; Y Guiot; A Everard; O Rottier; L Geurts; D Naslain; A Neyrinck; D M Lambert; G G Muccioli; N M Delzenne
Journal:  Gut       Date:  2009-02-24       Impact factor: 23.059

Review 9.  Therapeutic options in pediatric non alcoholic fatty liver disease: current status and future directions.

Authors:  Pietro Vajro; Selvaggia Lenta; Claudio Pignata; Mariacarolina Salerno; Roberta D'Aniello; Ida De Micco; Giulia Paolella; Giancarlo Parenti
Journal:  Ital J Pediatr       Date:  2012-10-17       Impact factor: 2.638

10.  Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial.

Authors:  Wojciech Janczyk; Piotr Socha; Dariusz Lebensztejn; Aldona Wierzbicka; Artur Mazur; Joanna Neuhoff-Murawska; Pawel Matusik
Journal:  BMC Pediatr       Date:  2013-05-23       Impact factor: 2.125
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  13 in total

Review 1.  Nonalcoholic Fatty Liver Disease, the Gut Microbiome, and Diet.

Authors:  Zeinab Mokhtari; Deanna L Gibson; Azita Hekmatdoost
Journal:  Adv Nutr       Date:  2017-03-15       Impact factor: 8.701

Review 2.  Future of Treatment for Nonalcoholic Steatohepatitis: Can the Use of Safe, Evidence-Based, Clinically Proven Supplements Provide the Answer to the Unmet Need?

Authors:  Yaron Ilan
Journal:  Dig Dis Sci       Date:  2018-04-20       Impact factor: 3.199

Review 3.  The links between the gut microbiome and non-alcoholic fatty liver disease (NAFLD).

Authors:  Zahra Safari; Philippe Gérard
Journal:  Cell Mol Life Sci       Date:  2019-01-25       Impact factor: 9.207

Review 4.  Intestinal Microbiome Shifts, Dysbiosis, Inflammation, and Non-alcoholic Fatty Liver Disease.

Authors:  Emma T Saltzman; Talia Palacios; Michael Thomsen; Luis Vitetta
Journal:  Front Microbiol       Date:  2018-01-30       Impact factor: 5.640

5.  In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model.

Authors:  Antonietta Stellavato; Anna Virginia Adriana Pirozzi; Francesca de Novellis; Ilaria Scognamiglio; Valentina Vassallo; Andrea Maria Giori; Mario De Rosa; Chiara Schiraldi
Journal:  Lipids Health Dis       Date:  2018-02-05       Impact factor: 3.876

6.  Egg consumption and risk of non-alcoholic fatty liver disease.

Authors:  Zeinab Mokhtari; Hossein Poustchi; Tannaz Eslamparast; Azita Hekmatdoost
Journal:  World J Hepatol       Date:  2017-04-08

Review 7.  Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates.

Authors:  Rahim Ullah; Naveed Rauf; Ghulam Nabi; Hamid Ullah; Yi Shen; Yu-Dong Zhou; Junfen Fu
Journal:  Int J Biol Sci       Date:  2019-01-01       Impact factor: 6.580

8.  Telemonitoring-Supported Exercise Training in Employees With Metabolic Syndrome Improves Liver Inflammation and Fibrosis.

Authors:  Sven Haufe; Katharina L Hupa-Breier; Pauline Bayerle; Hedwig T Boeck; Simone Rolff; Thorben Sundermeier; Arno Kerling; Julian Eigendorf; Momme Kück; Alexander A Hanke; Ralf Ensslen; Lars Nachbar; Dirk Lauenstein; Dietmar Böthig; Denise Hilfiker-Kleiner; Meike Stiesch; Christoph Terkamp; Heiner Wedemeyer; Axel Haverich; Uwe Tegtbur
Journal:  Clin Transl Gastroenterol       Date:  2021-06-18       Impact factor: 4.488

9.  The effects of onion consumption on treatment of metabolic, histologic, and inflammatory features of nonalcoholic fatty liver disease.

Authors:  Hadi Emamat; Forough Foroughi; Hassan Eini-Zinab; Mohsen Taghizadeh; Marjan Rismanchi; Azita Hekmatdoost
Journal:  J Diabetes Metab Disord       Date:  2016-07-22

Review 10.  Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions.

Authors:  Maria Grazia Clemente; Claudia Mandato; Marco Poeta; Pietro Vajro
Journal:  World J Gastroenterol       Date:  2016-09-28       Impact factor: 5.742
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