Literature DB >> 26557588

Efficacy of Transcerebellar Diameter/Abdominal Circumference Versus Head Circumference/Abdominal Circumference in Predicting Asymmetric Intrauterine Growth Retardation.

Rashmi M Nagaraju1, Venkataramana Bhat2, Puttanna Vn Gowda3.   

Abstract

BACKGROUND: The high incidence of IUGR and its low recognition lead to increasing perinatal morbidity and mortality for which prediction of IUGR with timely management decisions is of paramount importance. Many studies have compared the efficacy of several gestational age independent parameters and found that TCD/AC is a better predictor of asymmetric IUGR. AIM: To compare the accuracy of transcerebellar diameter/abdominal circumference with head circumference/abdominal circumference in predicting asymmetric intrauterine growth retardation after 20 weeks of gestation.
MATERIALS AND METHODS: The prospective study was conducted over a period of one year on 50 clinically suspected IUGR pregnancies who were evaluated with 3.5 MHz frequency ultrasound scanner by a single sonologist. BPD, HC, AC and FL along with TCD were measured for assessing the sonological gestational age. Two morphometric ratios- TCD/AC and HC/AC were calculated. Estimated fetal weight was calculated for all these pregnancies and its percentile was determined. STATISTICAL METHODS: The TCD/AC and HC/AC ratios were correlated with advancing gestational age to know if these were related to GA. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy (DA) for TCD/AC and HC/AC ratios in evaluating IUGR fetuses were calculated.
RESULTS: In the present study, linear relation of TCD and HC in IUGR fetuses with gestation was noted. The sensitivity, specificity, PPV, NPV & DA were 88%, 93.5%, 77.1%, 96.3% & 92.4% respectively for TCD/AC ratio versus 84%, 92%, 72.4%, 95.8% & 90.4% respectively for HC/AC ratio in predicting IUGR.
CONCLUSION: Both ratios were gestational age independent and can be used in detecting IUGR with good diagnostic accuracy. However, TCD/AC ratio had a better diagnostic validity and accuracy compared to HC/AC ratio in predicting asymmetric IUGR.

Entities:  

Keywords:  Fetal cerebellum; Gestational age; Growth restriction; Ultrasound

Year:  2015        PMID: 26557588      PMCID: PMC4625307          DOI: 10.7860/JCDR/2015/14079.6554

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  15 in total

1.  Fetal transverse cerebellar diameter measurements in normal and reduced fetal growth.

Authors:  A S Vinkesteijn; P G Mulder; J W Wladimiroff
Journal:  Ultrasound Obstet Gynecol       Date:  2000-01       Impact factor: 7.299

2.  Fetal cerebellum: US appearance with advancing gestational age.

Authors:  K Hashimoto; T Shimizu; K Shimoya; T Kanzaki; J F Clapp; Y Murata
Journal:  Radiology       Date:  2001-10       Impact factor: 11.105

3.  Transverse cerebellar diameter/abdominal circumference ratio throughout pregnancy: a gestational age-independent method to assess fetal growth.

Authors:  W A Campbell; D Nardi; A M Vintzileos; J F Rodis; G W Turner; J F Egan
Journal:  Obstet Gynecol       Date:  1991-06       Impact factor: 7.661

4.  Fetal transcerebellar diameter measurement for prediction of gestational age at the extremes of fetal growth.

Authors:  Martin R Chavez; Cande V Ananth; John C Smulian; Anthony M Vintzileos
Journal:  J Ultrasound Med       Date:  2007-09       Impact factor: 2.153

5.  Fetal cerebellar growth unaffected by intrauterine growth retardation: a new parameter for prenatal diagnosis.

Authors:  E A Reece; I Goldstein; G Pilu; J C Hobbins
Journal:  Am J Obstet Gynecol       Date:  1987-09       Impact factor: 8.661

6.  Biometric and dynamic ultrasound assessment of small-for-dates infants: report of 260 cases.

Authors:  A Kurjak; P Kirkinen; V Latin
Journal:  Obstet Gynecol       Date:  1980-09       Impact factor: 7.661

7.  Intrauterine growth retardation: diagnosis based on multiple parameters--a prospective study.

Authors:  C B Benson; J S Belville; J F Lentini; D H Saltzman; P M Doubilet
Journal:  Radiology       Date:  1990-11       Impact factor: 11.105

8.  Reference centile charts for ratio of fetal transverse cerebellar diameter to abdominal circumference in a Thai population.

Authors:  Nitsana Singhakom; Saifon Chawanpaiboon; Vitaya Titapant
Journal:  J Med Assoc Thai       Date:  2004-10

9.  Ratios between the abdominal circumference, head circumference, or femur length and the transverse cerebellar diameter of the growth-retarded and macrosomic fetus.

Authors:  L M Hill; D Guzick; D DiNofrio; J Maloney; C Merolillo; P Nedzesky
Journal:  Am J Perinatol       Date:  1994-03       Impact factor: 1.862

10.  Ultrasonographic detection of abnormal fetal growth with the gestational age-independent, transverse cerebellar diameter/abdominal circumference ratio.

Authors:  W J Meyer; D Gauthier; V Ramakrishnan; J Sipos
Journal:  Am J Obstet Gynecol       Date:  1994-10       Impact factor: 8.661

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  1 in total

1.  Hepato - Cephalic Index as a Predictor of Intrauterine Growth Restriction.

Authors:  Ramadan Dacaj; Sebija Izetbegovic; Goran Stojkanovic; Curr Gjocaj
Journal:  Acta Inform Med       Date:  2016-02-02
  1 in total

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