Literature DB >> 26557552

Morning Glory Disc Anomaly, A Report of a Successfully Treated Case of Functional Amblyopia.

Humberto Cavazos-Adame1, Abraham Olvera-Barrios2, Alejandro Martinez-Lopez-Portillo3, Jesus Mohamed-Hamsho4.   

Abstract

Morning Glory Disc Anomaly (MGDA) is a congenital malformation of the optic nerve characterized by the presence of a funnel-shaped macropapilla with neuroglial remnants in its center surrounded by an elevated and pigmented chorioretinal ring. Its incidence is rare and no gender predisposition has been found. Associated conditions like strabismus lead to an early diagnosis. We report the case of a 3.8-year-old boy with amblyopia of the right eye (count fingers 0.3 meters) due to MGDA. Correction of the refractive error with glasses, along with occlusive therapy resulted in a visual acuity of 20/100 after a five-year follow up. The presence of amblyopia in these cases demands an early management oriented to improve the visual acuity. Every patient with an anatomical malformation diagnosed during the period of sensory maturation should be treated with occlusive therapy and followed on a regular basis to diagnose associated conditions such as retinal detachment. We recommend occlusive therapy in every patient diagnosed with MGDA or in any patient with unilateral or asymmetric structural abnormalities that could lead to amblyopia. This 5-year case follow-up provides additional evidence of the importance of treatment during the period of amblyopia reversibility.

Entities:  

Keywords:  Morning glory disc syndrome; Optic nerve dysplasia; Organic amblyopia; Relative amblyopia; Strabismus

Year:  2015        PMID: 26557552      PMCID: PMC4625271          DOI: 10.7860/JCDR/2015/15086.6695

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  15 in total

1.  Mutations of the PAX6 gene detected in patients with a variety of optic-nerve malformations.

Authors:  Noriyuki Azuma; Yuki Yamaguchi; Hiroshi Handa; Keiko Tadokoro; Atsuko Asaka; Eriko Kawase; Masao Yamada
Journal:  Am J Hum Genet       Date:  2003-04-29       Impact factor: 11.025

Review 2.  Update on the morning glory disc anomaly.

Authors:  Brian J Lee; Elias I Traboulsi
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Authors:  Paul Harasymowycz; Lyne Chevrette; Jean-Claude Décarie; Nelly Hanna; Maryam Aroichane; Jean-Louis Jacob; Jean Milot; Magda Homsy
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2005 Sep-Oct       Impact factor: 1.402

4.  Retinal arteriovenous communications in the morning glory disc anomaly.

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Journal:  Arch Ophthalmol       Date:  1995-04

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Review 6.  Midline craniofacial defects and morning glory disc anomaly. A distinct clinical entity.

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Journal:  Acta Ophthalmol Scand Suppl       Date:  1996

7.  [Retinal detachment associated with morning glory syndrome].

Authors:  C Cañete Campos; P Gili Manzanaro; J Yangüela Rodilla; J C Martín Rodrigo
Journal:  Arch Soc Esp Oftalmol       Date:  2011-07-16

Review 8.  Congenital optic disk anomalies.

Authors:  M C Brodsky
Journal:  Surv Ophthalmol       Date:  1994 Sep-Oct       Impact factor: 6.048

9.  Visual insignificance of the foveal pit: reassessment of foveal hypoplasia as fovea plana.

Authors:  Michael F Marmor; Stacey S Choi; Robert J Zawadzki; John S Werner
Journal:  Arch Ophthalmol       Date:  2008-07

10.  [Rehabilitation on functional amblyopia in Morning Glory Syndrome].

Authors:  C Loudot; C Fogliarini; C Baeteman; J Mancini; N Girard; D Denis
Journal:  J Fr Ophtalmol       Date:  2007-12       Impact factor: 0.818

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  2 in total

1.  MORNING GLORY SYNDROME IN A NIGERIAN - A CASE REPORT.

Authors:  V B Osaguona; R O Momoh
Journal:  J West Afr Coll Surg       Date:  2017 Jan-Mar

2.  A Rare Case of Unilateral Morning Glory Disc Anomaly in a Patient with Turner Syndrome: Report and Review of Posterior Segment Associations.

Authors:  Dev R Sahni; Michael Wallace; Mansi Kanhere; Hind Al Saif; Natario Couser
Journal:  Case Rep Ophthalmol Med       Date:  2018-06-28
  2 in total

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