Literature DB >> 26556781

Longtime undetected microcystic adnexal carcinoma of the scalp: considerations and implications.

Christian Kühn1, Christina Schnabl1, Jan Rustemeyer2.   

Abstract

BACKGROUND: Microcystic adnexal carcinomas (MACs) are slow-growing and often asymptomatic malignant skin tumours that usually develop on the facial skin and may reach considerable size. We present an uncommon case of MAC arising on the hair-bearing scalp and discuss our experiences and considerations. CASE REPORT: A 58-year-old female was admitted with a histopathologically secured diagnosis of MAC of the temporal and occipital regions that had expanded to 10 × 12 cm. Magnetic resonance imaging revealed an infiltration of the skin and the subcutaneous adipose tissue. No lymphatic or haematogenic metastases were detected. Therapy consisted of resecting the tumour and reconstructing the area by applying an anterolateral thigh (ALT) flap. Histopathological evaluation revealed clear, 1-cm margins and a tumour-free periosteum. One-year postoperative follow-ups showed no evidence of recurrence, while the outcome was aesthetically pleasing.
CONCLUSION: When screening for skin cancer, careful attention must be paid to the scalp. Resection of MAC with clear margins is mandatory to minimize the risk of recurrence. In this case, applying an ALT perforator flap to a large defect of the hair-bearing scalp led to a very satisfying result; it should be considered in comparable cases.

Entities:  

Keywords:  Anterolateral thigh flap; Magnetic resonance imaging; Microcystic adnexal carcinoma; Skin cancer; Skin cancer screening

Mesh:

Year:  2015        PMID: 26556781     DOI: 10.1007/s10006-015-0534-1

Source DB:  PubMed          Journal:  Oral Maxillofac Surg        ISSN: 1865-1550


  11 in total

Review 1.  Microcystic adnexal carcinoma: a diagnostic and therapeutic challenge.

Authors:  Robyn Wetter; Glenn D Goldstein
Journal:  Dermatol Ther       Date:  2008 Nov-Dec       Impact factor: 2.851

2.  Microcystic adnexal carcinoma: successful management of a large scalp lesion.

Authors:  Lawrence H C Kim; Leana Teston; Sanaz Sasani; Christopher Henderson
Journal:  J Plast Surg Hand Surg       Date:  2013-08-23

3.  Microcystic adnexal carcinoma: forty-eight cases, their treatment, and their outcome.

Authors:  K Chiller; D Passaro; M Scheuller; M Singer; T McCalmont; R C Grekin
Journal:  Arch Dermatol       Date:  2000-11

4.  Survival after resection of cutaneous adnexal carcinomas with eccrine differentiation: risk factors and trends in outcomes.

Authors:  Jacob B Avraham; Dana Villines; Vijay K Maker; Carey August; Ajay V Maker
Journal:  J Surg Oncol       Date:  2013-05-16       Impact factor: 3.454

5.  Microcystic adnexal carcinoma: a distinct clinicopathologic entity.

Authors:  D J Goldstein; R J Barr; D J Santa Cruz
Journal:  Cancer       Date:  1982-08-01       Impact factor: 6.860

6.  Benign subclinical syringomatous proliferations adjacent to a microcystic adnexal carcinoma: a tumor mimic with significant patient implications.

Authors:  Markus D Boos; Rosalie Elenitsas; John Seykora; Michael S Lehrer; Christopher J Miller; Joseph Sobanko
Journal:  Am J Dermatopathol       Date:  2014-02       Impact factor: 1.533

7.  Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin.

Authors:  James B Yu; Rachel C Blitzblau; Sonya C Patel; Roy H Decker; Lynn D Wilson
Journal:  Am J Clin Oncol       Date:  2010-04       Impact factor: 2.339

8.  A comparison of free anterolateral thigh and latissimus dorsi flaps in soft tissue reconstruction of extensive defects in the head and neck region.

Authors:  Dominik Horn; Rene Jonas; Michael Engel; Kolja Freier; Jürgen Hoffmann; Christian Freudlsperger
Journal:  J Craniomaxillofac Surg       Date:  2013-11-20       Impact factor: 2.078

9.  Microcystic adnexal carcinoma simulating scarring alopecia.

Authors:  Maria Christina Marques Nogueira Castanon; Sandra Maria Gasparete Casali; Raul Fernando Binato Lamim; Marina Vieira Nagahama; Camila Bastos Xavier Vassimon Silva; Rafael Guerra Nannetti de Carvalho
Journal:  An Bras Dermatol       Date:  2015 May-Jun       Impact factor: 1.896

10.  Microcystic adnexal carcinoma: reconstruction of a large centrofacial defect.

Authors:  Mariela Lopez; Eric L Cole
Journal:  Plast Reconstr Surg Glob Open       Date:  2014-12-05
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