Literature DB >> 26555601

The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype.

Scott A Kelly1, Fernando Pardo-Manuel de Villena2, Daniel Pomp3.   

Abstract

Predisposition to engage in exercise is highly variable and simultaneously influenced by the environment, complex genomics, and their interactions. Given the importance of exercise to health, understanding the underlying influences of variability is crucial. Here, we discuss murine systems approaches, focusing on 'omics', relevant to revealing the architecture of voluntary activity.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Collaborative Cross; Diversity Outbred; genomics; proteomics; transcriptomics; wheel running

Mesh:

Year:  2015        PMID: 26555601     DOI: 10.1016/j.tem.2015.10.002

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN: 1043-2760            Impact factor:   12.015


  3 in total

1.  CC002/Unc females are mouse models of exercise-induced paradoxical fat response.

Authors:  Rachel C McMullan; Martin T Ferris; Timothy A Bell; Vineet D Menachery; Ralph S Baric; Kunjie Hua; Daniel Pomp; Abbie E Smith-Ryan; Fernando Pardo-Manuel de Villena
Journal:  Physiol Rep       Date:  2018-06

2.  Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection.

Authors:  Elissa J Chesler; Daniel M Gatti; Andrew P Morgan; Marge Strobel; Laura Trepanier; Denesa Oberbeck; Shannon McWeeney; Robert Hitzemann; Martin Ferris; Rachel McMullan; Amelia Clayshultle; Timothy A Bell; Fernando Pardo Manuel de Villena; Gary A Churchill
Journal:  G3 (Bethesda)       Date:  2016-12-07       Impact factor: 3.154

Review 3.  Targeting mitochondrial phenotypes for non-communicable diseases.

Authors:  Zhengtang Qi; Shuzhe Ding
Journal:  J Sport Health Sci       Date:  2016-04-07       Impact factor: 7.179

  3 in total

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