Literature DB >> 26555295

Erratum to: Vitamin D regulating TGF-β induced epithelial-mesenchymal transition.

Kimberly D Fischer1, Devendra K Agrawal2,3.   

Abstract

Entities:  

Year:  2015        PMID: 26555295      PMCID: PMC4641412          DOI: 10.1186/s12931-015-0301-8

Source DB:  PubMed          Journal:  Respir Res        ISSN: 1465-9921


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Erratum

After publication of the original article [1], it came to the authors’ attention that Fig. 8, associated with the wound healing assay to show the migration of the cells following scratch, inadvertently placed the same representative images in both experimental groups (TGF-β1 + calcitriol and TGF-β2 + calcitriol) at 0H and 48H to indicate two different treatment groups. The 0H and 48H time point pictures representing TGF-β2 and calcitriol treatment groups were the same pictures used in the images denoting 0H and 48H time points for the TGF-β1 and calcitriol treatment group.
Fig. 8

Calcitriol inhibits the migration of TGF-β stimulated BEAS-2B cells. BEAS-2B cells were stimulated with 100 nM calcitriol for 24 h followed by 48 h of stimulation by 10 ng/ml of TGF-β1 or TGF-β2. a Representative images of a wound healing scratch assay. Pictures of the same area were taken at 0 and 48 h at 20x magnification. The area of the wound was measured using the NIH ImageJ program. b The % wound closure was calculated and means of groups were compared by one-way ANOVA. Data is presented as mean ± SEM (n =4), *p <0.05 and **p <0.01 compared to control, ## p <0.01 compared to calcitriol treated cells, § p <0.05, §§ p <0.01

Calcitriol inhibits the migration of TGF-β stimulated BEAS-2B cells. BEAS-2B cells were stimulated with 100 nM calcitriol for 24 h followed by 48 h of stimulation by 10 ng/ml of TGF-β1 or TGF-β2. a Representative images of a wound healing scratch assay. Pictures of the same area were taken at 0 and 48 h at 20x magnification. The area of the wound was measured using the NIH ImageJ program. b The % wound closure was calculated and means of groups were compared by one-way ANOVA. Data is presented as mean ± SEM (n =4), *p <0.05 and **p <0.01 compared to control, ## p <0.01 compared to calcitriol treated cells, § p <0.05, §§ p <0.01 The image duplication occurred when the images were used as a placeholder for forthcoming data. The choice of image was independent of data analysis and thus does not change the results of this study. The correct image for Fig. 8 is shown below. The authors sincerely apologize for the inadvertent error and the inconvenience to the journal and the readers.
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1.  Vitamin D regulating TGF-β induced epithelial-mesenchymal transition.

Authors:  Kimberly D Fischer; Devendra K Agrawal
Journal:  Respir Res       Date:  2014-11-21
  1 in total
  1 in total

1.  1&#945;,25-dihydroxyvitamin D3 Attenuates TGF-&#946;-Induced Pro-Fibrotic Effects in Human Lung Epithelial Cells through Inhibition of Epithelial-Mesenchymal Transition.

Authors:  Fei Jiang; Yong Yang; Lian Xue; Bingyan Li; Zengli Zhang
Journal:  Nutrients       Date:  2017-09-06       Impact factor: 5.717

  1 in total

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