Literature DB >> 26553385

Is somatosensory amplification a risk factor for an increased report of side effects? Reference data from the German general population.

B K Doering1, Y Nestoriuc2, A J Barsky3, H Glaesmer4, E Brähler5, W Rief6.   

Abstract

OBJECTIVE: The study investigates the association between somatosensory amplification and the reporting of side effects. It establishes a German version of the Somatosensory Amplification Scale and examines its psychometric properties in a representative sample of the German population.
METHODS: Sample size was 2.469, with 51% taking any medication. Participants answered the Somatosensory Amplification Scale, Generic Assessment of Side Effects Scale, and indicated whether they were taking any medication and the type of medication. Correlational analysis and binary logistic regression were performed.
RESULTS: When examining a subsample reporting both medication intake and general bodily symptoms, participants higher in somatosensory amplification rated more of their general bodily symptoms as medication-attributed side effects. However, somatosensory amplification scores were not associated with the intake of any type of medication. In the overall sample, higher somatosensory amplification scores were associated with an increased report of bodily symptoms. Additionally, participants with higher somatosensory amplification reported intake of a greater number of different medications. The psychometric properties of the translated scale were good, and previously established associations of somatosensory amplification with demographic variables (age, sex) were replicated.
CONCLUSION: Results suggest a possible attributional bias concomitant to somatosensory amplification which in turn may increase the reporting of side effects after medication intake.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adverse effects; Nocebo; Reference data; Side effects; Somatosensory amplification

Mesh:

Year:  2015        PMID: 26553385     DOI: 10.1016/j.jpsychores.2015.10.010

Source DB:  PubMed          Journal:  J Psychosom Res        ISSN: 0022-3999            Impact factor:   3.006


  2 in total

1.  Somatosensory Amplification Is a Predictor of Self-Reported Side Effects in the Treatment of Primary Hypertension: a Pilot Study.

Authors:  Bettina K Doering; Judit Szécsi; György Bárdos; Ferenc Köteles
Journal:  Int J Behav Med       Date:  2016-06

2.  A test of positive suggestions about side effects as a way of enhancing the analgesic response to NSAIDs.

Authors:  Aurore Fernandez; Irving Kirsch; Louis Noël; Pierre Yves Rodondi; Ted J Kaptchuk; Marc R Suter; Isabelle Décosterd; Chantal Berna
Journal:  PLoS One       Date:  2019-01-03       Impact factor: 3.240

  2 in total

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