Literature DB >> 265530

Lymphocyte mitogenesis induced by a mammalian liver protein that specifically binds desialylated glycoproteins.

A Novogrodsky, G Ashwell.   

Abstract

A purified rabbit liver membrane protein that binds desialylated glycoproteins has been shown to be a mitogen for human peripheral lymphocytes. The mitogenic activity is specific for desialylated thymus-derived (T)-cells. The loss of mitogenicity upon exposure of the binding protein to neuraminidase and the inhibitory potency of asialo-orosomucoid support the conclusion that the site involved in the binding of asialoglycoproteins is also responsible for the mitogenic effect on desialylated lymphocytes. The potential relevance of this phenomenon to the etiology of hepatocellular necrosis is considered.

Entities:  

Mesh：

Substances：

Year:  1977        PMID： 265530      PMCID： PMC392355          DOI： 10.1073/pnas.74.2.676

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  17 in total

1.  Chemical and physical properties of an hepatic membrane protein that specifically binds asialoglycoproteins.

Authors:  T Kawasaki; G Ashwell
Journal:  J Biol Chem       Date:  1976-03-10       Impact factor: 5.157

Review 2.  The biochemistry of plant lectins (phytohemagglutinins).

Authors:  H Lis; N Sharon
Journal:  Annu Rev Biochem       Date:  1973       Impact factor: 23.643

3.  The isolation and properties of a rabbit liver binding protein specific for asialoglycoproteins.

Authors:  R L Hudgin; W E Pricer; G Ashwell; R J Stockert; A G Morell
Journal:  J Biol Chem       Date:  1974-09-10       Impact factor: 5.157

4.  Studies on the chemical and enzymatic modification of glycoproteins. A general method for the tritiation of sialic acid-containing glycoproteins.

Authors:  L Van Lenten; G Ashwell
Journal:  J Biol Chem       Date:  1971-03-25       Impact factor: 5.157

Review 5.  Cytotoxic effects of lymphoid cells in vitro.

Authors:  P Perlmann; G Holm
Journal:  Adv Immunol       Date:  1969       Impact factor: 3.543

6.  Transformation of neuraminidase-treated lymphocytes by soybean agglutinin.

Authors:  A Novogrodsky; E Katchalski
Journal:  Proc Natl Acad Sci U S A       Date:  1973-09       Impact factor: 11.205

7.  Histocompatibility matching. VI. Miniaturization of the mixed leukocyte culture test: a preliminary report.

Authors:  R J Hartzman; M Segall; M L Bach; F H Bach
Journal:  Transplantation       Date:  1971-03       Impact factor: 4.939

8.  Influenza A virus interaction with murine lymphocytes. II. Changes in lymphocyte surface properties induced by influenza virus A/Japan 305 (H2N2).

Authors:  J J Woodruff; J F Woodruff
Journal:  J Immunol       Date:  1976-09       Impact factor: 5.422

9.  The purification, composition, and specificity of the anti-T lectin from peanut (Arachis hypogaea).

Authors:  R Lotan; E Skutelsky; D Danon; N Sharon
Journal:  J Biol Chem       Date:  1975-11-10       Impact factor: 5.157

10.  Cellular interactions in the proliferative response of human T and B lymphocytes to phytomitogens and allogeneic lymphocytes.

Authors:  H P Lohrmann; L Novikovs; R G Graw
Journal:  J Exp Med       Date:  1974-06-01       Impact factor: 14.307
View more
  10 in total

1.  "Stuck on sugars - how carbohydrates regulate cell adhesion, recognition, and signaling".

Authors:  Richard D Cummings
Journal:  Glycoconj J       Date:  2019-07-02       Impact factor: 2.916

Review 2.  GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics.

Authors:  Aaron D Springer; Steven F Dowdy
Journal:  Nucleic Acid Ther       Date:  2018-05-24       Impact factor: 5.486

3.  [Glycoproteins: their biological and clinical significance. II (author's transl)].

Authors:  E Köttgen; C Bauer; W Reutter; W Gerok
Journal:  Klin Wochenschr       Date:  1979-03-01

Review 4.  The role of the liver in clearance of glycoproteins from the general circulation, with special reference to intestinal alkaline phosphatase.

Authors:  D K Meijer; H B Scholtens; M J Hardonk
Journal:  Pharm Weekbl Sci       Date:  1982-06-25

5.  Immunological function of adhesive glycoprotein from rat ascites hepatoma cells: production of macrophage chemotactic lymphokine.

Authors:  M Hifumi; H Hayashi
Journal:  Immunology       Date:  1983-06       Impact factor: 7.397

Review 6.  Structure, biosynthesis and functions of glycoprotein glycans.

Authors:  E G Berger; E Buddecke; J P Kamerling; A Kobata; J C Paulson; J F Vliegenthart
Journal:  Experientia       Date:  1982-10-15

7.  Studies of mammary carcinoma metastasis in a mouse model system. II: Lectin binding properties of cells in relation to the incidence and organ distribution of metastases.

Authors:  S C Barnett; S A Eccles
Journal:  Clin Exp Metastasis       Date:  1984 Oct-Dec       Impact factor: 5.150

8.  Dose responses for Colletotrichum lindemuthianum elicitor-mediated enzyme induction in French bean cell suspension cultures.

Authors:  R A Dixon; P M Dey; D L Murphy; I M Whitehead
Journal:  Planta       Date:  1981-03       Impact factor: 4.116

9.  Host-pathogen interactions in plants. Plants, when exposed to oligosaccharides of fungal origin, defend themselves by accumulating antibiotics.

Authors:  P Albersheim; B S Valent
Journal:  J Cell Biol       Date:  1978-09       Impact factor: 10.539

10.  Rat lymphocyte mitogenesis by aggregation factor from rat ascites hepatoma cell surface.

Authors:  J Kuratsu; M Yoshinaga; H Hayashi
Journal:  Br J Cancer       Date:  1978-08       Impact factor: 7.640
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.