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Literature DB >> 26551969

Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.

Nasim Annabi^1,2,3,4, Su Ryon Shin^1,2,3, Ali Tamayol^1,2,3, Mario Miscuglio^1,2, Mohsen Afshar Bakooshli^1,2, Alexander Assmann^1,2,3,5, Pooria Mostafalu^1,2, Jeong-Yun Sun⁶, Suzanne Mithieux⁷, Louis Cheung⁸, Xiaowu Shirley Tang⁸, Anthony S Weiss⁷, Ali Khademhosseini^1,2,3,9.

Abstract

A highly elastic hybrid hydrogel of methacryloyl-substituted recombinant human tropoelastin (MeTro) and graphene oxide (GO) nanoparticles are developed. The synergistic effect of these two materials significantly enhances both ultimate strain (250%), reversible rotation (9700°), and the fracture energy (38.8 ± 0.8 J m(-2) ) in the hybrid network. Furthermore, improved electrical signal propagation and subsequent contraction of the muscles connected by hybrid hydrogels are observed in ex vivo tests.

Entities: Chemical Disease Gene Species

Keywords: cardiac tissue engineering; elasticity; graphene oxides; hydrogels; tropoelastins

Mesh：

Substances：

Year: 2015 PMID： 26551969 PMCID： PMC4863466 DOI： 10.1002/adma.201503255

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

40 in total

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4. Biodegradable nanofibrous polymeric substrates for generating elastic and flexible electronics.

Authors: Alireza Hassani Najafabadi; Ali Tamayol; Nasim Annabi; Manuel Ochoa; Pooria Mostafalu; Mohsen Akbari; Mehdi Nikkhah; Rahim Rahimi; Mehmet R Dokmeci; Sameer Sonkusale; Babak Ziaie; Ali Khademhosseini
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5. In vitro toxicity evaluation of graphene oxide on A549 cells.

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9. Nanowired three-dimensional cardiac patches.

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10. Probing mechanoregulation of neuronal differentiation by plasma lithography patterned elastomeric substrates.

Authors: Ki-Hwan Nam; Nima Jamilpour; Etienne Mfoumou; Fei-Yue Wang; Donna D Zhang; Pak Kin Wong
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37 in total

1. Mussel-Inspired Multifunctional Hydrogel Coating for Prevention of Infections and Enhanced Osteogenesis.

Authors: Hao Cheng; Kan Yue; Mehdi Kazemzadeh-Narbat; Yanhui Liu; Akbar Khalilpour; Bingyun Li; Yu Shrike Zhang; Nasim Annabi; Ali Khademhosseini
Journal: ACS Appl Mater Interfaces Date: 2017-03-21 Impact factor: 9.229

2. Biodegradable Gelatin Methacryloyl Microneedles for Transdermal Drug Delivery.

Authors: Zhimin Luo; Wujin Sun; Jun Fang; KangJu Lee; Song Li; Zhen Gu; Mehmet R Dokmeci; Ali Khademhosseini
Journal: Adv Healthc Mater Date: 2018-12-19 Impact factor: 9.933

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7. Gold Nanocomposite Bioink for Printing 3D Cardiac Constructs.

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