Literature DB >> 26551551

Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk.

Guan-Huei Lee1, Boon-Huan Tan2, Esmeralda Chi-Yuan Teo3, Seng-Gee Lim4, Yock-Young Dan4, Aileen Wee5, Pauline Poh Kim Aw6, Yuan Zhu6, Martin Lloyd Hibberd7, Chee-Kiat Tan8, Michael A Purdy9, Chong-Gee Teo9.   

Abstract

There have been increasing reports of food-borne zoonotic transmission of hepatitis E virus (HEV) genotype 3, which causes chronic infections in immunosuppressed patients. We performed phylogenetic analyses of the HEV sequence (partial and full-length) from 1 patient from the Middle East who underwent liver transplantation, and compared it with other orthohepevirus A sequences. We found the patient to be infected by camelid HEV. This patient regularly consumed camel meat and milk, therefore camelid HEV, which is genotype 7, might infect human beings. Our finding links consumption of camel-derived food products to post-transplantation hepatitis E, which, if detected at early stages, can be cured with antiviral therapy and reduced administration of immunosuppressive agents.
Copyright © 2016 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Case Study; Liver Disease; Viral Infection; Zoonosis

Mesh:

Substances:

Year:  2015        PMID: 26551551     DOI: 10.1053/j.gastro.2015.10.048

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  155 in total

Review 1.  Acute and Persistent Hepatitis E Virus Genotype 3 and 4 Infection: Clinical Features, Pathogenesis, and Treatment.

Authors:  Nassim Kamar; Sven Pischke
Journal:  Cold Spring Harb Perspect Med       Date:  2019-07-01       Impact factor: 6.915

Review 2.  Small Animal Models of Hepatitis E Virus Infection.

Authors:  Tian-Cheng Li; Takaji Wakita
Journal:  Cold Spring Harb Perspect Med       Date:  2019-08-01       Impact factor: 6.915

3.  Hepatitis E Virus in Surface Water, Sediments, and Pork Products Marketed in Southern Brazil.

Authors:  F H Heldt; R Staggmeier; J S Gularte; M Demoliner; A Henzel; F R Spilki
Journal:  Food Environ Virol       Date:  2016-05-12       Impact factor: 2.778

4.  CD8+ lymphocytes but not B lymphocytes are required for protection against chronic hepatitis E virus infection in chickens.

Authors:  Eda Rogers; Stephanie Michelle Todd; Frank William Pierson; Scott P Kenney; Connie Lynn Heffron; Danielle M Yugo; Shannon R Matzinger; Elena Mircoff; Irene Ngo; Charles Kirby; Michaela Jones; Paul Siegel; Peter Jobst; Karen Hall; Robert J Etches; Xiang-Jin Meng; Tanya LeRoith
Journal:  J Med Virol       Date:  2019-07-25       Impact factor: 2.327

Review 5.  Clinical features and determinants of chronicity in hepatitis E virus infection.

Authors:  Shivakumar Narayanan; Ameer Abutaleb; Kenneth E Sherman; Shyam Kottilil
Journal:  J Viral Hepat       Date:  2019-02-05       Impact factor: 3.728

6.  Antiviral Candidates for Treating Hepatitis E Virus Infection.

Authors:  Natalie E Netzler; Daniel Enosi Tuipulotu; Subhash G Vasudevan; Jason M Mackenzie; Peter A White
Journal:  Antimicrob Agents Chemother       Date:  2019-05-24       Impact factor: 5.191

7.  Infection Dynamics of Hepatitis E Virus in Wild-Type and Immunoglobulin Heavy Chain Knockout JH -/- Gnotobiotic Piglets.

Authors:  Danielle M Yugo; C Lynn Heffron; Junghyun Ryu; Kyungjun Uh; Sakthivel Subramaniam; Shannon R Matzinger; Christopher Overend; Dianjun Cao; Scott P Kenney; Harini Sooryanarain; Thomas Cecere; Tanya LeRoith; Lijuan Yuan; Nathaniel Jue; Sherrie Clark-Deener; Kiho Lee; Xiang-Jin Meng
Journal:  J Virol       Date:  2018-10-12       Impact factor: 5.103

8.  Pan-Genotype Hepatitis E Virus Replication in Stem Cell-Derived Hepatocellular Systems.

Authors:  Xianfang Wu; Viet Loan Dao Thi; Peng Liu; Constantin N Takacs; Kuanhui Xiang; Linda Andrus; Jérôme Gouttenoire; Darius Moradpour; Charles M Rice
Journal:  Gastroenterology       Date:  2017-12-24       Impact factor: 22.682

9.  The Enigma of Hepatitis E Virus.

Authors:  Liza Bronner Murrison; Kenneth E Sherman
Journal:  Gastroenterol Hepatol (N Y)       Date:  2017-08

10.  Transmission of a Novel Genotype of Hepatitis E Virus from Bactrian Camels to Cynomolgus Macaques.

Authors:  Lin Wang; Jade L L Teng; Susanna K P Lau; Siddharth Sridhar; Hongwei Fu; Wanyun Gong; Manyu Li; Qieshi Xu; Yunye He; Hui Zhuang; Patrick C Y Woo; Ling Wang
Journal:  J Virol       Date:  2019-03-21       Impact factor: 5.103

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