Literature DB >> 26550378

Efficacy of methylprednisolone sodium succinate for injection (postotic injection) on the auditory threshold and speech recognition rate of sudden deafness patients.

Xin Li1, Xiao-Yan Zhang2, Qiu-Ju Wang3, Da-Yong Wang3.   

Abstract

OBJECTIVE: To investigate the effect of injecting the methylprednisolone in the ear for the sudden deafness and the improvement of speech discrimination test.
METHODS: 50 inpatients with a sudden hearing loss were recruited. Inject the methylprednisolone in the subperiosteal of the ear which is 0.5 cm distance to the ear ditch every three days. Methylprednisolone was placed for fifteen days. Simultaneously vasodilation, neurotrophic, thrombolysis and insulin hypoglycemia were administered in all patients. Pure tone test and speech discrimination test were conducted at Days 7 & 14 after intervention.
RESULTS: The outcome was as follows: cure (n = 8), efficacy (n = 9), effect (n = 18) and no effect (n = 15) respectively. The overall effective rate of 70%. The improvement of pure tone threshold and speech discrimination had significant statistical difference (P < 0.05).
CONCLUSION: The therapy of postaural methylprednisolone injection can decrease pure tone threshold effectively and increased speech discrimination with a sudden hearing loss.

Entities:  

Keywords:  Postaurical injection; methylprednisolone; speech discrimination test; sudden deafness

Year:  2015        PMID: 26550378      PMCID: PMC4613063     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  5 in total

1.  Prognostic factors of sudden sensorineural hearing loss in diabetic patients.

Authors:  Shuen-Fu Weng; Yuh-Shyang Chen; Tien-Chen Liu; Chuan-Jen Hsu; Fen-Yu Tseng
Journal:  Diabetes Care       Date:  2004-10       Impact factor: 19.112

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Review 5.  Idiopathic sudden sensorineural hearing loss: etiopathogenic aspects.

Authors:  Paulo Roberto Lazarini; Ana Cristina Kfouri Camargo
Journal:  Braz J Otorhinolaryngol       Date:  2006 Jul-Aug
  5 in total
  7 in total

1.  Postauricular injection of methylprednisolone sodium succinate as a salvage treatment for refractory sudden sensorineural hearing loss.

Authors:  Gang Ren; Jue Xu; Longjiang Lan; Bingliang Ma; Qi Zhang
Journal:  Ir J Med Sci       Date:  2021-04-17       Impact factor: 1.568

2.  Comparison between Bilateral and Unilateral Sudden Sensorineural Hearing Loss.

Authors:  Dan Bing; Da-Yong Wang; Lan Lan; Li-Dong Zhao; Zi-Fang Yin; Lan Yu; Guo-Hui Chen; Jing Guan; Qiu-Ju Wang
Journal:  Chin Med J (Engl)       Date:  2018-02-05       Impact factor: 2.628

3.  Effects of surgery and topical medication on eosinophilic granulomatosis with polyangiitis with otitis media and sinusitis: a case report.

Authors:  Zijing Wang; Lin Han; Lisheng Yu
Journal:  J Int Med Res       Date:  2020-04       Impact factor: 1.671

4.  Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss.

Authors:  Yuhua Zhu; Dan Bing; Dayong Wang; Lidong Zhao; Zifang Yin; Qiujing Zhang; Jing Guan; Qiuju Wang
Journal:  World J Otorhinolaryngol Head Neck Surg       Date:  2020-04-29

5.  Comparison of the Pathway to the Inner Ear Between Postauricular and Intramuscular Injection of Dexamethasone in Guinea Pigs.

Authors:  Aiping Chen; Wenwen Liu; Lei Xu; Zhiqiang Hou; Zhaomin Fan; Haibo Wang; Mingming Wang
Journal:  Front Neurol       Date:  2022-03-04       Impact factor: 4.003

6.  Clinical Efficacy of Retroauricular Injection of Methylprednisolone Sodium Succinate in the Treatment of Sudden Deafness with Type 2 Diabetes.

Authors:  Zhenbo Zhong; Xiaofei Wang; Kairui Xu; Jing Tao
Journal:  Comput Math Methods Med       Date:  2022-07-22       Impact factor: 2.809

7.  Postaurical injection is a systemic delivery supported by symmetric distribution of Gd-DOTA in both the ipsilateral and contralateral ears.

Authors:  Jing Zou
Journal:  J Otol       Date:  2016-01-29
  7 in total

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