Jin Qiao1, Xiyuan Zheng2, Xiaoyan Wang3, Wenhui Lu1, Hongmei Cao1, Xing Qin1. 1. Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University Xi'an City 710061, Shaanxi Province, China. 2. Department of Neurology, The Second Affiliated Hospital of Xi'an Medical University Xi'an City 710038, Shaanxi Province, China. 3. Department of Medical Administration, The First Affiliated Hospital of Xi'an Jiaotong University Xi'an City 710061, Shaanxi Province, China.
Abstract
OBJECT: Cognitive impairments have been reported to be more common in non-demented patients with Parkinson's disease (PD) and education levels play an important role in intelligence. The studies on cognitive impairments in Chinese PD patients with higher education levels and normal global cognition according to Mini-Mental State Examination Score (MMSE) have not been reported. METHODS: We enrolled 69 consecutive PD patients with over 6 years education levels and a MMSE score above 24 (of 30) and performed a battery of neuropsychological scales. RESULTS: There are extensive cognitive domain impairments in PD patients with "normal" global cognitive according to MMSE. Montreal Cognitive Assessment (MoCA) is a highly sensitive scale to screen cognitive impairments in PD. CONCLUSION: The cutoff score of 28 on the MMSE screening for cognitive impairment in Chinese PD patients with high education levels may be more appropriate.
OBJECT: Cognitive impairments have been reported to be more common in non-demented patients with Parkinson's disease (PD) and education levels play an important role in intelligence. The studies on cognitive impairments in Chinese PDpatients with higher education levels and normal global cognition according to Mini-Mental State Examination Score (MMSE) have not been reported. METHODS: We enrolled 69 consecutive PDpatients with over 6 years education levels and a MMSE score above 24 (of 30) and performed a battery of neuropsychological scales. RESULTS: There are extensive cognitive domain impairments in PDpatients with "normal" global cognitive according to MMSE. Montreal Cognitive Assessment (MoCA) is a highly sensitive scale to screen cognitive impairments in PD. CONCLUSION: The cutoff score of 28 on the MMSE screening for cognitive impairment in Chinese PDpatients with high education levels may be more appropriate.
Entities:
Keywords:
Parkinson’s disease; cognitive impairment; mini-mental state examination; montreal cognitive assessment scale; neuropsychology
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