| Literature DB >> 26548588 |
Attilio Marino1,2, Jonathan Barsotti1,2, Giuseppe de Vito3,4, Carlo Filippeschi1, Barbara Mazzolai1, Vincenzo Piazza3, Massimiliano Labardi5, Virgilio Mattoli1, Gianni Ciofani1,6.
Abstract
In this letter, we report on the fabrication, the characterization, and the in vitro testing of structures suitable for cell culturing, prepared through two-photon polymerization of a nanocomposite resist. More in details, commercially available Ormocomp has been doped with piezoelectric barium titanate nanoparticles, and bioinspired 3D structures resembling trabeculae of sponge bone have been fabricated. After an extensive characterization, preliminary in vitro testing demonstrated that both the topographical and the piezoelectric cues of these scaffolds are able to enhance the differentiation process of human SaOS-2 cells.Entities:
Keywords: barium titanate nanoparticles; bone tissue engineering; direct laser writing; piezoelectric stimulation; two-photon lithography
Mesh：
Year: 2015 PMID： 26548588 DOI： 10.1021/acsami.5b08764
Source DB: PubMed Journal: ACS Appl Mater Interfaces ISSN： 1944-8244 Impact factor: 9.229