Rut Navarro-Martínez1, Julio Fernández-Garrido1, Cristina Buigues1, Mary Martinez-Martinez2, Liliana Cantero-Díaz2, Yolanda Santamaría-Carrillo3, Nuria Serra-Catalá3, Carlos Peris4, Omar Cauli5. 1. Department of Medical Nursing, Faculty of Nursing, University of Valencia, 46010 Valencia, Spain. 2. Centro municipal para personas mayores "Arniches", 46014 Valencia, Spain. 3. Centro municipal para personas mayores "Arniches", 46014 Valencia, Spain; GeroResidencias La Saleta, 46015 Valencia, Spain. 4. GeroResidencias La Saleta, 46015 Valencia, Spain. 5. Department of Medical Nursing, Faculty of Nursing, University of Valencia, 46010 Valencia, Spain. Electronic address: Omar.Cauli@uv.es.
Abstract
PURPOSE: Serum vitamin D deficiency has been associated with frailty in people aged 65 and over, however its relationship with functional impairment has not been investigated in octogenerian (aged 80-90 years) institutionalized women. METHODS: We assessed functional impairment in this latter group by measuring frailty syndrome and other geriatric and psychological assessment scales: the Tinetti gait and balance index to determine the risk for falls, the Barthel index to measure the basic activities of daily living, the Lawton index for instrumental activities, the mini-mental score examination test for cognitive impairment, the Yesavage scale for geriatric depression, and the Norton scale for the risk of ulceration. RESULTS: Frail individuals had significantly reduced serum vitamin D concentrations (measured as total 25-hydroxyvitamin D; 25(OH)D) compared to robust individuals, but reduced 25(OH)D concentration did not significantly correlate with frailty syndrome severity, and mean 25(OH)D concentrations were within the recommended levels in all groups. The 25(OH)D concentration did not correlate with any of the blood analytical parameters measured and with the geriatric assessment scales used, suggesting a selective relationship with frailty. CONCLUSION: These results highlight the need to individualize treatment such as vitamin D supplementation in order to treat frailty syndrome.
PURPOSE: Serum vitamin D deficiency has been associated with frailty in people aged 65 and over, however its relationship with functional impairment has not been investigated in octogenerian (aged 80-90 years) institutionalized women. METHODS: We assessed functional impairment in this latter group by measuring frailty syndrome and other geriatric and psychological assessment scales: the Tinetti gait and balance index to determine the risk for falls, the Barthel index to measure the basic activities of daily living, the Lawton index for instrumental activities, the mini-mental score examination test for cognitive impairment, the Yesavage scale for geriatric depression, and the Norton scale for the risk of ulceration. RESULTS: Frail individuals had significantly reduced serum vitamin D concentrations (measured as total 25-hydroxyvitamin D; 25(OH)D) compared to robust individuals, but reduced 25(OH)D concentration did not significantly correlate with frailty syndrome severity, and mean 25(OH)D concentrations were within the recommended levels in all groups. The 25(OH)D concentration did not correlate with any of the blood analytical parameters measured and with the geriatric assessment scales used, suggesting a selective relationship with frailty. CONCLUSION: These results highlight the need to individualize treatment such as vitamin D supplementation in order to treat frailty syndrome.
Authors: Orlagh Feehan; David J Armstrong; Pamela J Magee; Kirsty L Pourshahidi; J J Strain; Laura Beggan; Diego F Cobice; Emeir M McSorley Journal: Nutrients Date: 2022-06-28 Impact factor: 6.706
Authors: Sofia Cardoso; Alejandro Santos; Rita S Guerra; Ana S Sousa; Patrícia Padrão; Pedro Moreira; Cláudia Afonso; Teresa F Amaral; Nuno Borges Journal: BMC Geriatr Date: 2017-10-31 Impact factor: 3.921