Lukas Filli1, Soleen Ghafoor2, David Kenkel2, Wei Liu3, Elisabeth Weiland4, Gustav Andreisek2, Thomas Frauenfelder2, Val M Runge5, Andreas Boss2. 1. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland. Electronic address: Lukas.Filli@usz.ch. 2. Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Switzerland. 3. Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China. 4. MR Application Development, Siemens Healthcare, Erlangen, Germany. 5. Inselspital, Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie, Bern, Switzerland.
Abstract
OBJECTIVES: Readout-segmented echo planar imaging (rs-EPI) significantly reduces susceptibility artifacts in diffusion-weighted imaging (DWI) of the breast compared to single-shot EPI but is limited by longer scan times. To compensate for this, we tested a new simultaneous multi-slice (SMS) acquisition for accelerated rs-EPI. MATERIALS AND METHODS: After approval by the local ethics committee, eight healthy female volunteers (age, 38.9 ± 13.1 years) underwent breast MRI at 3T. Conventional as well as two-fold (2× SMS) and three-fold (3× SMS) slice-accelerated rs-EPI sequences were acquired at b-values of 50 and 800 s/mm(2). Two independent readers analyzed the apparent diffusion coefficient (ADC) in fibroglandular breast parenchyma. The signal-to-noise ratio (SNR) was estimated based on the subtraction method. ADC and SNR were compared between sequences by using the Friedman test. RESULTS: The acquisition time was 4:21 min for conventional rs-EPI, 2:35 min for 2× SMS rs-EPI and 1:44 min for 3× SMS rs-EPI. ADC values were similar in all sequences (mean values 1.62 × 10(-3)mm(2)/s, p=0.99). Mean SNR was 27.7-29.6, and no significant differences were found among the sequences (p=0.83). CONCLUSION: SMS rs-EPI yields similar ADC values and SNR compared to conventional rs-EPI at markedly reduced scan time. Thus, SMS excitation increases the clinical applicability of rs-EPI for DWI of the breast.
OBJECTIVES: Readout-segmented echo planar imaging (rs-EPI) significantly reduces susceptibility artifacts in diffusion-weighted imaging (DWI) of the breast compared to single-shot EPI but is limited by longer scan times. To compensate for this, we tested a new simultaneous multi-slice (SMS) acquisition for accelerated rs-EPI. MATERIALS AND METHODS: After approval by the local ethics committee, eight healthy female volunteers (age, 38.9 ± 13.1 years) underwent breast MRI at 3T. Conventional as well as two-fold (2× SMS) and three-fold (3× SMS) slice-accelerated rs-EPI sequences were acquired at b-values of 50 and 800 s/mm(2). Two independent readers analyzed the apparent diffusion coefficient (ADC) in fibroglandular breast parenchyma. The signal-to-noise ratio (SNR) was estimated based on the subtraction method. ADC and SNR were compared between sequences by using the Friedman test. RESULTS: The acquisition time was 4:21 min for conventional rs-EPI, 2:35 min for 2× SMS rs-EPI and 1:44 min for 3× SMS rs-EPI. ADC values were similar in all sequences (mean values 1.62 × 10(-3)mm(2)/s, p=0.99). Mean SNR was 27.7-29.6, and no significant differences were found among the sequences (p=0.83). CONCLUSION:SMS rs-EPI yields similar ADC values and SNR compared to conventional rs-EPI at markedly reduced scan time. Thus, SMS excitation increases the clinical applicability of rs-EPI for DWI of the breast.
Authors: Katja Pinker; Linda Moy; Elizabeth J Sutton; Ritse M Mann; Michael Weber; Sunitha B Thakur; Maxine S Jochelson; Zsuzsanna Bago-Horvath; Elizabeth A Morris; Pascal At Baltzer; Thomas H Helbich Journal: Invest Radiol Date: 2018-10 Impact factor: 6.016
Authors: Fabian Tollens; Pascal A T Baltzer; Matthias Dietzel; Moritz L Schnitzer; Vincent Schwarze; Wolfgang G Kunz; Johann Rink; Johannes Rübenthaler; Matthias F Froelich; Stefan O Schönberg; Clemens G Kaiser Journal: Eur Radiol Date: 2022-04-28 Impact factor: 5.315
Authors: Debosmita Biswas; Daniel S Hippe; Yi Wang; Michaela R DelPriore; Mladen Zečević; John R Scheel; Habib Rahbar; Savannah C Partridge Journal: Radiol Imaging Cancer Date: 2022-01
Authors: Jessica A McKay; An L Church; Nathan Rubin; Tim H Emory; Noelle F Hoven; Jessica E Kuehn-Hajder; Michael T Nelson; Sudhir Ramanna; Edward J Auerbach; Steen Moeller; Patrick J Bolan Journal: Radiology Date: 2020-08-25 Impact factor: 11.105
Authors: Alexander Ciritsis; Cristina Rossi; Magda Marcon; Valerie Doan Phi Van; Andreas Boss Journal: Medicine (Baltimore) Date: 2018-08 Impact factor: 1.889