Literature DB >> 26546520

Review: The Role of Insulin-like Growth Factor-1 Signaling Pathways in Uterine Leiomyoma.

Eliona Gkioka1, Pavlos Msaouel2, Anastassios Philippou1, Nikolaos I Vlaghogiannis1, Christiana T Vogkou1, Argyris Margiolis3, Michael Koutsilieris4.   

Abstract

A growing body of evidence suggests the association of the IGF-I bio-regulatory system with leiomyoma occurrence and growth. The complex interplay between IGF-I/IGF-IR and hormonal and other growth factors is, thus, now receiving significant attention. Elucidation of the molecular mechanisms driving the disease may allow for development of novel targeted-therapeutic strategies for the treatment of leiomyomas. Herein, we provide a concise update and overview of the function and regulation of IGF-I and its role in leiomyoma growth.
Copyright © 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Entities:  

Keywords:  IGFs; Leiomyomas; estrogen receptor; progesterone receptor; review

Mesh：

Substances：

Year:  2015        PMID： 26546520

Source DB:  PubMed          Journal:  In Vivo        ISSN： 0258-851X            Impact factor:   2.155


  9 in total

1.  Cellular kinetics of MED12-mutant uterine leiomyoma growth and regression in vivo.

Authors:  Vanida A Serna; Xin Wu; Wenan Qiang; Justin Thomas; Michael L Blumenfeld; Takeshi Kurita
Journal:  Endocr Relat Cancer       Date:  2018-04-26       Impact factor: 5.678

2.  Insulin-like growth factor-1 receptor expression in upper tract urothelial carcinoma.

Authors:  Marie-Lisa Eich; Aline C Tregnago; Sheila F Faraj; Doreen N Palsgrove; Kazutoshi Fujita; Stephania M Bezerra; Enrico Munari; Rajni Sharma; Alcides Chaux; George J Netto
Journal:  Virchows Arch       Date:  2018-10-18       Impact factor: 4.064

3.  The risk of hypertension and cardiovascular disease in women with uterine fibroids.

Authors:  Yentl C Haan; Frederieke S Diemer; Lisa Van Der Woude; Gert A Van Montfrans; Glenn P Oehlers; Lizzy M Brewster
Journal:  J Clin Hypertens (Greenwich)       Date:  2018-03-22       Impact factor: 3.738

Review 4.  Wnt/β-catenin signaling pathway in uterine leiomyoma: role in tumor biology and targeting opportunities.

Authors:  Malak El Sabeh; Subbroto Kumar Saha; Sadia Afrin; Md Soriful Islam; Mostafa A Borahay
Journal:  Mol Cell Biochem       Date:  2021-05-17       Impact factor: 3.842

5.  Oncomirs Expression Profiling in Uterine Leiomyosarcoma Cells.

Authors:  Bruna Cristine de Almeida; Natalia Garcia; Giovana Maffazioli; Laura Gonzalez dos Anjos; Edmund Chada Baracat; Katia Candido Carvalho
Journal:  Int J Mol Sci       Date:  2017-12-25       Impact factor: 5.923

6.  Copy number variation (CNV) in the IGF1R gene across four cattle breeds and its association with economic traits.

Authors:  Yi-Lei Ma; Yi-Fan Wen; Xiu-Kai Cao; Jie Cheng; Yong-Zhen Huang; Yun Ma; Lin-Yong Hu; Chu-Zhao Lei; Xing-Lei Qi; Hui Cao; Hong Chen
Journal:  Arch Anim Breed       Date:  2019-04-11

7.  Stem Cell Growth and Differentiation in Organ Culture: New Insights for Uterine Fibroid Treatment.

Authors:  Ana Salas; Silvia Beltrán-Flores; Carmen Évora; Ricardo Reyes; Francisco Montes de Oca; Araceli Delgado; Teresa A Almeida
Journal:  Biomedicines       Date:  2022-06-29

Review 8.  Cardiometabolic Risk Factors and Benign Gynecologic Disorders.

Authors:  Abdelrahman AlAshqar; Kristin Patzkowsky; Sadia Afrin; Robert Wild; Hugh S Taylor; Mostafa A Borahay
Journal:  Obstet Gynecol Surv       Date:  2019-11       Impact factor: 2.347

9.  Could miRNA Signatures be Useful for Predicting Uterine Sarcoma and Carcinosarcoma Prognosis and Treatment?

Authors:  Laura Gonzalez Dos Anjos; Bruna Cristine de Almeida; Thais Gomes de Almeida; André Mourão Lavorato Rocha; Giovana De Nardo Maffazioli; Fernando Augusto Soares; Isabela Werneck da Cunha; Edmund Chada Baracat; Katia Candido Carvalho
Journal:  Cancers (Basel)       Date:  2018-09-06       Impact factor: 6.639
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.