Tormod Karlsen Bjånes1, Espen Mjåset Hjertø2, Lars Lønne2, Lena Aronsen3, Jon Andsnes Berg4, Stein Bergan5, Grim Otto Berg-Hansen6, Jean-Paul Bernard7, Margrete Larsen Burns5, Jan Toralf Fosen6, Joachim Frost8, Thor Hilberg9, Hege-Merete Krabseth5, Elena Kvan10, Sigrid Narum7, Andreas Austgulen Westin8. 1. Laboratory of Clinical Biochemistry, Section of Clinical Pharmacology, Haukeland University Hospital, Bergen, Norway. Electronic address: tormod.karlsen.bjanes@helse-bergen.no. 2. Kantega AS, Trondheim, Norway. 3. Clinical Pharmacology, Department of Laboratory Medicine, University Hospital of North Norway, Tromsø, Norway. 4. Laboratory of Clinical Biochemistry, Section of Clinical Pharmacology, Haukeland University Hospital, Bergen, Norway. 5. Department of Pharmacology, Oslo University Hospital, Oslo, Norway. 6. Norwegian Institute of Public Health, Division of Forensic Medicine, Oslo, Norway. 7. The Centre for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway. 8. Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway. 9. Fürst Medical Laboratory, Oslo, Norway. 10. Department of Medical Biochemistry, Vestre Viken Hospital Trust, Drammen, Norway.
Abstract
PURPOSE: More than 50 Norwegian public and private laboratories provide one or more analyses for therapeutic drug monitoring or testing for drugs of abuse. Practices differ among laboratories, and analytical repertoires can change rapidly as new substances become available for analysis. METHODS: The Pharmacology Portal was developed to provide an overview of these activities and to standardize the practices and terminology among laboratories. The Pharmacology Portal is a modern dynamic web database comprising all available analyses within therapeutic drug monitoring and testing for drugs of abuse in Norway. Content can be retrieved by using the search engine or by scrolling through substance lists. The core content is a substance registry updated by a national editorial board of experts within the field of clinical pharmacology. This ensures quality and consistency regarding substance terminologies and classification. FINDINGS: All laboratories publish their own repertoires in a user-friendly workflow, adding laboratory-specific details to the core information in the substance registry. The user management system ensures that laboratories are restricted from editing content in the database core or in repertoires within other laboratory subpages. The portal is for nonprofit use, and has been fully funded by the Norwegian Medical Association, the Norwegian Society of Clinical Pharmacology, and the 8 largest pharmacologic institutions in Norway. IMPLICATIONS: The database server runs an open-source content management system that ensures flexibility with respect to further development projects, including the potential expansion of the Pharmacology Portal to other countries.
PURPOSE: More than 50 Norwegian public and private laboratories provide one or more analyses for therapeutic drug monitoring or testing for drugs of abuse. Practices differ among laboratories, and analytical repertoires can change rapidly as new substances become available for analysis. METHODS: The Pharmacology Portal was developed to provide an overview of these activities and to standardize the practices and terminology among laboratories. The Pharmacology Portal is a modern dynamic web database comprising all available analyses within therapeutic drug monitoring and testing for drugs of abuse in Norway. Content can be retrieved by using the search engine or by scrolling through substance lists. The core content is a substance registry updated by a national editorial board of experts within the field of clinical pharmacology. This ensures quality and consistency regarding substance terminologies and classification. FINDINGS: All laboratories publish their own repertoires in a user-friendly workflow, adding laboratory-specific details to the core information in the substance registry. The user management system ensures that laboratories are restricted from editing content in the database core or in repertoires within other laboratory subpages. The portal is for nonprofit use, and has been fully funded by the Norwegian Medical Association, the Norwegian Society of Clinical Pharmacology, and the 8 largest pharmacologic institutions in Norway. IMPLICATIONS: The database server runs an open-source content management system that ensures flexibility with respect to further development projects, including the potential expansion of the Pharmacology Portal to other countries.