Literature DB >> 26546400

Natural Products as Source of Therapeutics against Parasitic Diseases.

Christian Hertweck1,2.   

Abstract

An end to suffering: Parasitic infections with protozoa and worms cause unimaginable misery, in particular in the tropics. Fortunately, natural products, such as the antimalarial artemisinin (1) and the anthelmintic avermectin (2) were discovered and developed into therapeutics. These major achievements now culminated in the 2015 Nobel Prize for Medicine.
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  Nobel Prize; antiparasitics; artemisinin; avermectin; malaria; natural products

Mesh：

Substances：

Year:  2015        PMID： 26546400     DOI： 10.1002/anie.201509828

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  10 in total

1.  Assessment of the antiprotozoal activity of Pulicaria inuloides extracts, an Algerian medicinal plant: leishmanicidal bioguided fractionation.

Authors:  Hamza Fadel; Ines Sifaoui; Atteneri López-Arencibia; María Reyes-Batlle; Soumaya Hajaji; Olfa Chiboub; Ignacio A Jiménez; Isabel L Bazzocchi; Jacob Lorenzo-Morales; Samir Benayache; José E Piñero
Journal:  Parasitol Res       Date:  2018-01-06       Impact factor: 2.289

2.  Dual regulation between the two-component system PhoRP and AdpA regulates antibiotic production in Streptomyces.

Authors:  Yang Zheng; Chen-Fan Sun; Yu Fu; Xin-Ai Chen; Yong-Quan Li; Xu-Ming Mao
Journal:  J Ind Microbiol Biotechnol       Date:  2019-02-02       Impact factor: 3.346

3.  Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.

Authors:  Swapna Johnson; Raphaël Rahmani; Damien R Drew; Melanie J Williams; Mark Wilkinson; Yan Hong Tan; Johnny X Huang; Christopher J Tonkin; James G Beeson; Jake Baum; Brian J Smith; Jonathan B Baell
Journal:  J Med Chem       Date:  2016-12-02       Impact factor: 7.446

Review 4.  Repurposing strategies for tropical disease drug discovery.

Authors:  Dana M Klug; Michael H Gelb; Michael P Pollastri
Journal:  Bioorg Med Chem Lett       Date:  2016-03-30       Impact factor: 2.823

Review 5.  Applications of Nonenzymatic Catalysts to the Alteration of Natural Products.

Authors:  Christopher R Shugrue; Scott J Miller
Journal:  Chem Rev       Date:  2017-06-05       Impact factor: 60.622

6.  In Vitro Antimalarial and Toxicological Activities of Quercus infectoria (Olivier) Gall Extracts.

Authors:  Nik Nor Imam Nik Mat Zin; Mira Nabila Mohamad; Keusar Roslan; Sazeli Abdul Wafi; Nurul I'zaaz Abdul Moin; Azamuddin Alias; Yusmazura Zakaria; Nurhidanatasha Abu-Bakar
Journal:  Malays J Med Sci       Date:  2020-08-19

7.  The Eighth Central European Conference "Chemistry towards Biology": Snapshot.

Authors:  András Perczel; Atanas G Atanasov; Vladimír Sklenář; Jiří Nováček; Veronika Papoušková; Pavel Kadeřávek; Lukáš Žídek; Henryk Kozłowski; Joanna Wątły; Aleksandra Hecel; Paulina Kołkowska; Jaroslav Koča; Radka Svobodová-Vařeková; Lukáš Pravda; David Sehnal; Vladimír Horský; Stanislav Geidl; Ricardo D Enriz; Pavel Matějka; Adéla Jeništová; Marcela Dendisová; Alžběta Kokaislová; Volkmar Weissig; Mark Olsen; Aidan Coffey; Jude Ajuebor; Ruth Keary; Marta Sanz-Gaitero; Mark J van Raaij; Olivia McAuliffe; Birgit Waltenberger; Andrei Mocan; Karel Šmejkal; Elke H Heiss; Marc Diederich; Robert Musioł; Janez Košmrlj; Jarosław Polański; Josef Jampílek
Journal:  Molecules       Date:  2016-10-17       Impact factor: 4.411

8.  A Systematic Review of Recently Reported Marine Derived Natural Product Kinase Inhibitors.

Authors:  Te Li; Ning Wang; Ting Zhang; Bin Zhang; Thavarool P Sajeevan; Valsamma Joseph; Lorene Armstrong; Shan He; Xiaojun Yan; C Benjamin Naman
Journal:  Mar Drugs       Date:  2019-08-23       Impact factor: 5.118

Review 9.  Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders.

Authors:  Birgit Waltenberger; Andrei Mocan; Karel Šmejkal; Elke H Heiss; Atanas G Atanasov
Journal:  Molecules       Date:  2016-06-22       Impact factor: 4.411

Review 10.  A Review of Quercus infectoria (Olivier) Galls as a Resource for Anti-parasitic Agents: In Vitro and In Vivo Studies.

Authors:  Nik Nor Imam Nik Mat Zin; Wan Nur Addiena Wan Mohd Rahimi; Nurhidanatasha Abu Bakar
Journal:  Malays J Med Sci       Date:  2019-12-30
  10 in total

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