| Literature DB >> 26546040 |
Douglas W Strand1, LaTayia Aaron2, Gervaise Henry1, Omar E Franco3, Simon W Hayward4.
Abstract
The use of lineage tracing in transgenic mouse models has revealed an abundance of subcellular phenotypes responsible for maintaining prostate homeostasis. The ability to use fresh human tissues to examine the hypotheses generated by these mouse experiments has been greatly enhanced by technical advances in tissue processing, flow cytometry and cell culture. We describe in detail the optimization of protocols for each of these areas to facilitate research on solving human prostate diseases through the analysis of human tissue.Entities:
Mesh:
Year: 2015 PMID: 26546040 PMCID: PMC4854811 DOI: 10.1016/j.diff.2015.10.013
Source DB: PubMed Journal: Differentiation ISSN: 0301-4681 Impact factor: 3.880