| Literature DB >> 26545809 |
C Philandrianos1, N Kerfant2, C Jaloux3, L Martinet4, B Bertrand3, D Casanova3.
Abstract
Keloid scars are a dysregulated response to cutaneous wound healing and are characterized by excessive deposition of collagen. Clinical and histological aspects are typical but they are often confused with hypertrophic scars. Principal pathogenesis is abnormal regulation of the collagen equilibrium because of TGFβ. In this first part, clinical characteristics, physiopathology and histology of keloid scars are explained.Entities:
Keywords: Chéloïde; Cicatrice; Collagen bundle; Collagène hyalin; Fibroblast; Fibroblaste; Fibrose; Fibrosis; Keloid; Scar; TGFβ
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Year: 2015 PMID: 26545809 DOI: 10.1016/j.anplas.2015.09.005
Source DB: PubMed Journal: Ann Chir Plast Esthet ISSN: 0294-1260 Impact factor: 0.660