Changwei Liu1, Mi Lu2, Xiaona Xia3, Jingwen Wang3, Yuanyuan Wan3, Lianping He4, Mei Li5. 1. Nanjing Children's Hospital Affiliated to Nanjing Medical University (Nanjing), Jiangsu.. 1983helianping@163.com. 2. School of Medical Imaging and laboratory, Wannan Medical College (Wuhu), Anhui.. lumi0503@163.com. 3. Nanjing Children's Hospital Affiliated to Nanjing Medical University (Nanjing), Jiangsu.. 597888447@qq.com. 4. School of Public Health, Wannan Medical College (Wuhu), Anhui. China.. 1983helianping@163.com. 5. Nanjing Children's Hospital Affiliated to Nanjing Medical University (Nanjing), Jiangsu.. limeilimei6868@126.com.
Abstract
OBJECTIVE: to assess the relationship between serums vitamin D level and type 1 diabetes mellitus (T1DM) in children. METHODS: the following electronic databases were searched until Sep 2014 to identify relevant studies that assessed the relationship between serum vitamin D with T1DM: PubMed\EMbase\Medline\Central Register of Controlled Trials\CBM\Chinese National Knowledge Infrastructure (CNKI)\wangfang; The NOS scale was used to evaluate the quality of studies, and the statistical tests were performed by Stata 11.0 software. RESULT: a total of 10 studies were included in this study. Our results showed that serum vitamin D was significantly lower in children with T1DM than in healthy controls (MD = -0.60, P < 0.05). No evidence support publication bias in present study. CONCLUSION: the meta-analysis suggests that serum vitamin D level is associated with T1DM in children. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
OBJECTIVE: to assess the relationship between serums vitamin D level and type 1 diabetes mellitus (T1DM) in children. METHODS: the following electronic databases were searched until Sep 2014 to identify relevant studies that assessed the relationship between serum vitamin D with T1DM: PubMed\EMbase\Medline\Central Register of Controlled Trials\CBM\Chinese National Knowledge Infrastructure (CNKI)\wangfang; The NOS scale was used to evaluate the quality of studies, and the statistical tests were performed by Stata 11.0 software. RESULT: a total of 10 studies were included in this study. Our results showed that serum vitamin D was significantly lower in children with T1DM than in healthy controls (MD = -0.60, P < 0.05). No evidence support publication bias in present study. CONCLUSION: the meta-analysis suggests that serum vitamin D level is associated with T1DM in children. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
Authors: Ahmed El-Abd Ahmed; Hala M Sakhr; Mohammed H Hassan; Mostafa I El-Amir; Hesham H Ameen Journal: Diabetes Metab Syndr Obes Date: 2019-05-14 Impact factor: 3.168