| Literature DB >> 26544931 |
Abstract
Germline stem cells divide asymmetrically, producing a self-renewing stem cell and a differentiating progenitor. Xie et al. now show that this depends on two asymmetric events that together partition a genome copy, carrying the old histones to the stem cell daughter and a copy with new, unmarked histones to the differentiating daughter.Mesh:
Substances:
Year: 2015 PMID: 26544931 DOI: 10.1016/j.cell.2015.10.043
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582