| Literature DB >> 26544111 |
Ciara Metcalfe1, Christian W Siebel2.
Abstract
The adult lung is largely quiescent, with airway epithelia turning over slowly. Peng et al. (2015) describe a key role for the Hedgehog pathway in actively maintaining this quiescence, a surprising turn of events given the pathway's established mitogenic role, and they show that Hedgehog pathway attenuation is required for proliferative regeneration.Entities:
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Year: 2015 PMID： 26544111 DOI： 10.1016/j.stem.2015.10.010
Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633