Literature DB >> 26543823

Atrial fibrillation in patients with diabetes: molecular mechanisms and therapeutic perspectives.

Francesco De Sensi1, Tom De Potter1, Alberto Cresti1, Silva Severi1, Günter Breithardt1.   

Abstract

Atrial fibrillation (AF) remains the most frequent sustained cardiac arrhythmia worldwide and its incidence increases with ageing, cardiovascular risk factors and comorbidities. Prevalence of diabetes mellitus (DM) is growing fast and is assuming pandemic proportions mostly due to overnutrition and sedentary habits. Experimental and clinical evidences suggest that DM and AF are strongly interconnected. The present review addresses in detail new molecular pathways implicated in the etiology of AF and their relevance for mechanism-based therapeutic strategies in this setting. Advances in risk stratification, drug therapy (i.e., novel anticoagulants) and catheter ablation are also described.

Entities:  

Keywords:  Atrial fibrillation (AF); anticoagulants; catheter ablation; diabetes mellitus (DM)

Year:  2015        PMID： 26543823      PMCID： PMC4609900          DOI： 10.3978/j.issn.2223-3652.2015.06.03

Source DB:  PubMed          Journal:  Cardiovasc Diagn Ther        ISSN： 2223-3652


  63 in total

1.  Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.

Authors:  Yejia Song; John C Shryock; Stefan Wagner; Lars S Maier; Luiz Belardinelli
Journal:  J Pharmacol Exp Ther       Date:  2006-03-24       Impact factor: 4.030

2.  Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF).

Authors:  Brian F Gage; Yan Yan; Paul E Milligan; Amy D Waterman; Robert Culverhouse; Michael W Rich; Martha J Radford
Journal:  Am Heart J       Date:  2006-03       Impact factor: 4.749

Review 3.  Diabetic cardiomyopathy, causes and effects.

Authors:  Sihem Boudina; Evan Dale Abel
Journal:  Rev Endocr Metab Disord       Date:  2010-03       Impact factor: 6.514

Review 4.  Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference.

Authors:  Paulus Kirchhof; Gregory Y H Lip; Isabelle C Van Gelder; Jeroen Bax; Elaine Hylek; Stefan Kaab; Ulrich Schotten; Karl Wegscheider; Giuseppe Boriani; Axel Brandes; Michael Ezekowitz; Hans Diener; Laurent Haegeli; Hein Heidbuchel; Deirdre Lane; Luis Mont; Stephan Willems; Paul Dorian; Maria Aunes-Jansson; Carina Blomstrom-Lundqvist; Maria Borentain; Stefanie Breitenstein; Martina Brueckmann; Nilo Cater; Andreas Clemens; Dobromir Dobrev; Sergio Dubner; Nils G Edvardsson; Leif Friberg; Andreas Goette; Michele Gulizia; Robert Hatala; Jenny Horwood; Lukas Szumowski; Lukas Kappenberger; Josef Kautzner; Angelika Leute; Trudie Lobban; Ralf Meyer; Jay Millerhagen; John Morgan; Felix Muenzel; Michael Nabauer; Christoph Baertels; Michael Oeff; Dieter Paar; Juergen Polifka; Ursula Ravens; Ludger Rosin; W Stegink; Gerhard Steinbeck; Panos Vardas; Alphons Vincent; Maureen Walter; Günter Breithardt; A John Camm
Journal:  Europace       Date:  2011-07-26       Impact factor: 5.214

5.  Diabetes mellitus, glycemic control, and risk of atrial fibrillation.

Authors:  Sascha Dublin; Nicole L Glazer; Nicholas L Smith; Bruce M Psaty; Thomas Lumley; Kerri L Wiggins; Richard L Page; Susan R Heckbert
Journal:  J Gen Intern Med       Date:  2010-04-20       Impact factor: 5.128

6.  Common variants in KCNN3 are associated with lone atrial fibrillation.

Authors:  Patrick T Ellinor; Kathryn L Lunetta; Nicole L Glazer; Arne Pfeufer; Alvaro Alonso; Mina K Chung; Moritz F Sinner; Paul I W de Bakker; Martina Mueller; Steven A Lubitz; Ervin Fox; Dawood Darbar; Nicholas L Smith; Jonathan D Smith; Renate B Schnabel; Elsayed Z Soliman; Kenneth M Rice; David R Van Wagoner; Britt-M Beckmann; Charlotte van Noord; Ke Wang; Georg B Ehret; Jerome I Rotter; Stanley L Hazen; Gerhard Steinbeck; Albert V Smith; Lenore J Launer; Tamara B Harris; Seiko Makino; Mari Nelis; David J Milan; Siegfried Perz; Tõnu Esko; Anna Köttgen; Susanne Moebus; Christopher Newton-Cheh; Man Li; Stefan Möhlenkamp; Thomas J Wang; W H Linda Kao; Ramachandran S Vasan; Markus M Nöthen; Calum A MacRae; Bruno H Ch Stricker; Albert Hofman; André G Uitterlinden; Daniel Levy; Eric Boerwinkle; Andres Metspalu; Eric J Topol; Aravinda Chakravarti; Vilmundur Gudnason; Bruce M Psaty; Dan M Roden; Thomas Meitinger; H-Erich Wichmann; Jacqueline C M Witteman; John Barnard; Dan E Arking; Emelia J Benjamin; Susan R Heckbert; Stefan Kääb
Journal:  Nat Genet       Date:  2010-02-21       Impact factor: 38.330

7.  Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality: the Framingham Heart Study.

Authors:  Thomas J Wang; Martin G Larson; Daniel Levy; Ramachandran S Vasan; Eric P Leip; Philip A Wolf; Ralph B D'Agostino; Joanne M Murabito; William B Kannel; Emelia J Benjamin
Journal:  Circulation       Date:  2003-05-27       Impact factor: 29.690

Review 8.  Status of the epidemiology of atrial fibrillation.

Authors:  William B Kannel; Emelia J Benjamin
Journal:  Med Clin North Am       Date:  2008-01       Impact factor: 5.456

9.  Catheter ablation of atrial fibrillation in patients with diabetes mellitus type 2: results from a randomized study comparing pulmonary vein isolation versus antiarrhythmic drug therapy.

Authors:  Giovanni B Forleo; Massimo Mantica; Lucia De Luca; Roberto Leo; Luca Santini; Stefania Panigada; Valerio De Sanctis; Augusto Pappalardo; Francesco Laurenzi; Andrea Avella; Michela Casella; Antonio Dello Russo; Francesco Romeo; Gemma Pelargonio; Claudio Tondo
Journal:  J Cardiovasc Electrophysiol       Date:  2008-09-03

10.  Consistency of safety and efficacy of new oral anticoagulants across subgroups of patients with atrial fibrillation.

Authors:  Jean-Christophe Lega; Laurent Bertoletti; Cyrielle Gremillet; Céline Chapelle; Patrick Mismetti; Michel Cucherat; Denis Vital-Durand; Silvy Laporte
Journal:  PLoS One       Date:  2014-03-12       Impact factor: 3.240
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  16 in total

1.  Atrial fibrillation prevalence and predictors in patients with diabetes: a cross-sectional screening study.

Authors:  Angela Hall; Andrew Robert John Mitchell; Lisa Ashmore; Carol Holland
Journal:  Br J Cardiol       Date:  2022-03-08

2.  Association of Atrial Fibrillation with Diabetes Mellitus, High Risk Comorbidities.

Authors:  Leonida Gherasim Md PhD PhD
Journal:  Maedica (Bucur)       Date:  2022-03

3.  The Safety and Efficacy of Rivaroxaban Compared with Warfarin in Patients with Atrial Fibrillation and Diabetes: A Systematic Review and Meta-analysis.

Authors:  Yang Hua; Jin-Yu Sun; Yue Su; Qiang Qu; Hong-Ye Wang; Wei Sun; Xiang-Qing Kong
Journal:  Am J Cardiovasc Drugs       Date:  2021-01       Impact factor: 3.571

4.  Dipeptidyl peptidase-4 inhibitor decreases the risk of atrial fibrillation in patients with type 2 diabetes: a nationwide cohort study in Taiwan.

Authors:  Chia-Yu Chang; Yung-Hsin Yeh; Yi-Hsin Chan; Jia-Rou Liu; Shang-Hung Chang; Hsin-Fu Lee; Lung-Sheng Wu; Kun-Chi Yen; Chi-Tai Kuo; Lai-Chu See
Journal:  Cardiovasc Diabetol       Date:  2017-12-19       Impact factor: 9.951

5.  Role of CHA2DS2-VASc score in predicting new-onset atrial fibrillation in patients with type 2 diabetes mellitus with and without hyperosmolar hyperglycaemic state: real-world data from a nationwide cohort.

Authors:  Wei-Syun Hu; Cheng-Li Lin
Journal:  BMJ Open       Date:  2018-03-22       Impact factor: 2.692

6.  Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats.

Authors:  Qingmiao Shao; Lei Meng; Sharen Lee; Gary Tse; Mengqi Gong; Zhiwei Zhang; Jichao Zhao; Yungang Zhao; Guangping Li; Tong Liu
Journal:  Cardiovasc Diabetol       Date:  2019-11-28       Impact factor: 9.951

Review 7.  Imaging Techniques for the Study of Fibrosis in Atrial Fibrillation Ablation: From Molecular Mechanisms to Therapeutical Perspectives.

Authors:  Francesco De Sensi; Diego Penela; David Soto-Iglesias; Antonio Berruezo; Ugo Limbruno
Journal:  J Clin Med       Date:  2021-05-24       Impact factor: 4.241

8.  Comparison of New-Onset Diabetes Mellitus among Patients with Atrial Fibrillation or Atrial Flutter.

Authors:  Wei Syun Hu; Cheng Li Lin
Journal:  Korean Circ J       Date:  2020-03-13       Impact factor: 3.243

9.  Difference in left atrial appendage remodeling between diabetic and nondiabetic patients with atrial fibrillation.

Authors:  Chaim Yosefy; Marina Pery; Roman Nevzorov; Xavier Piltz; Azriel Osherov; Jamal Jafari; Ronen Beeri; Enrique Gallego-Colon; Aner Daum; Vladimir Khalameizer
Journal:  Clin Cardiol       Date:  2019-11-22       Impact factor: 2.882

Review 10.  Latest Insights into Mechanisms behind Atrial Cardiomyopathy: It Is Not always about Ventricular Function.

Authors:  Bianca-Ana Dmour; Radu-Stefan Miftode; Dan Iliescu Halitchi; Dana Teodora Anton-Paduraru; Codruta-Olimpiada Iliescu Halitchi; Ionela-Larisa Miftode; Ovidiu Mitu; Alexandru-Dan Costache; Celina-Silvia Stafie; Irina Iuliana Costache
Journal:  Diagnostics (Basel)       Date:  2021-03-05
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